ID   E1F4V1_GIAIA            Unreviewed;       981 AA.
AC   E1F4V1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=GLP15_1416 {ECO:0000313|EMBL:EFO62509.1};
OS   Giardia intestinalis (strain P15) (Giardia lamblia).
OC   Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO62509.1, ECO:0000313|Proteomes:UP000008974};
RN   [1] {ECO:0000313|EMBL:EFO62509.1, ECO:0000313|Proteomes:UP000008974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P15 {ECO:0000313|EMBL:EFO62509.1,
RC   ECO:0000313|Proteomes:UP000008974};
RX   PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA   Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA   Andersson J.O., Svard S.G., Andersson B.;
RT   "Genome analysis and comparative genomics of a Giardia intestinalis
RT   assemblage E isolate.";
RL   BMC Genomics 11:543-543(2010).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFO62509.1}.
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DR   EMBL; ACVC01000180; EFO62509.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1F4V1; -.
DR   EnsemblProtists; EFO62509; EFO62509; GLP15_1416.
DR   VEuPathDB; GiardiaDB:GLP15_1416; -.
DR   OMA; LLIDMAC; -.
DR   OrthoDB; 5478881at2759; -.
DR   Proteomes; UP000008974; Unassembled WGS sequence.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR013713; XPO2_central.
DR   Pfam; PF08506; Cse1; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
FT   DOMAIN          21..106
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   981 AA;  108911 MW;  273DF138E4E7A1ED CRC64;
     MYSDIRELLL GTLDPSRVQA STDAIQKLKG SPEFANFLYS YMLDASNDEQ TRYLASIYFS
     QIFRSPLSHE QNVLMEFSQS TLHCFCTLPL KIRRVIKDCL AVTLNHLYQC GKLPNLYSDC
     ASLLYGVLRE NSIDPLTYQG VLTPDVLHIL SDIMFLMLPF PSHAATIELD DTVALKLKSV
     IGSTSELIIS LLTMATTCYA ASLRDQASFI AYQGFLHSLY SFLTSMYSLD DLPTIYNDKY
     LYIATSSVTF LDLKTLASQG FNLMDPIVAE VCKKILNMLC NSISAHSAEL EAHAPGVIKL
     LIDMACNYVT VTEHKTFNMV LTDILFHLHF FAEGLESQKH IYANAPQLMN QVIFSALRLT
     VSDFEAIEEE DHEYVCGLLS IGDSTSRRSA CEGILRTVCR ALPDARGVAM QKAQESIASL
     GQGQGTLEWF VSLCQALAFY RAVVIQQVSK FTGVSLIISD SNFSEFYATV IAPSLRLSYS
     ISSTESMELS AAKTLALCEV MHFVTDFRNI MTDDQFSEGL QALLRCLSCT HNNVSNSVLS
     SCLSTILKNC KHTNVIARLE PQFIQLLHTF LSPSSQGSST CLLLHSGTND VYVANAFAAV
     LRLVSQSMTI DAVVELAVLF FSFVFPTCLQ RRDRLKLVHK LFESLVVILN VISDRAISGN
     KTTPAVVNQM IKLFASLYSQ LENEEDWLPI YFQILSPLMQ IAALTDAFTE AHYPILFKEI
     LPMYINAASL QISASIPAYA LAMNSFVSLA VTHNRSLLNN TIAAPDGTST PCIQRIVQFG
     SKLVTISNFR LYGYGVLTNI ASLIPECVPM DAYANALDVA QKELNEIQLD RKLLGAVCQF
     FVQYACSCDP STINSAFIIE ELLTPFTKKA FLRDSITKDI AVLLTRLPVN QLDEAIKWDV
     LRCIGVLGGL VRRKVNLCSR SRVKEGEATD SEEKTITDGS ALFIELKEVR DTWPTVPVPQ
     GFLLAKHITD TIPFDFKNLS A
//