ID E1JCA2_ECOLX Unreviewed; 911 AA.
AC E1JCA2;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=ABC transporter, ATP-binding protein {ECO:0000313|EMBL:EFK66520.1};
GN ORFNames=HMPREF9347_04596 {ECO:0000313|EMBL:EFK66520.1};
OS Escherichia coli MS 124-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=679205 {ECO:0000313|EMBL:EFK66520.1, ECO:0000313|Proteomes:UP000003390};
RN [1] {ECO:0000313|EMBL:EFK66520.1, ECO:0000313|Proteomes:UP000003390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS 124-1 {ECO:0000313|EMBL:EFK66520.1,
RC ECO:0000313|Proteomes:UP000003390};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFK66520.1}.
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DR EMBL; ADWT01000055; EFK66520.1; -; Genomic_DNA.
DR RefSeq; WP_000149133.1; NZ_ADWT01000055.1.
DR AlphaFoldDB; E1JCA2; -.
DR Proteomes; UP000003390; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03230; ABC_DR_subfamily_A; 1.
DR Gene3D; 3.40.1710.10; abc type-2 transporter like domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR047651; ABC2_perm_RbbA.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR047817; ABC2_TM_bact-type.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; NF033858; ABC2_perm_RbbA; 1.
DR PANTHER; PTHR43038; ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1; 1.
DR PANTHER; PTHR43038:SF4; RIBOSOME-ASSOCIATED ATPASE; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51012; ABC_TM2; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EFK66520.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 716..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 766..789
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 795..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 884..906
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..248
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 277..507
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 683..909
FT /note="ABC transmembrane type-2"
FT /evidence="ECO:0000259|PROSITE:PS51012"
SQ SEQUENCE 911 AA; 100825 MW; B2B840C0843B0698 CRC64;
MTHLELVPVP PVAQLAGVSQ HYGKTVALNN ITLDIPARCM VGLIGPDGVG KSSLLSLISG
ARVIEQGNVM VLGGDMRDPK HRRDVCPRIA WMPQGLGKNL YHTLSVYENV DFFARLFGHD
KAEREVRINE LLTSTGLAPF RDRPAGKLSG GMKQKLGLCC ALIHDPELLI LDEPTTGVDP
LSRAQFWDLI DSIRQRQSNM SVLVATAYME EAERFDWLVA MNAGEVLATG SAEELRQQTQ
SATLEEAFIN LLPQAQRQAH QAVVIPPYQP ENAEIAIEAR DLTMRFGSFV AVDHVNFRIP
RGEIFGFLGS NGCGKSTTMK MLTGLLPASE GEAWLFGQPV DPKDIDTRRR VGYMSQAFSL
YNELTVRQNL ELHARLFHIP EAEIPARVAE MSERFKLNDV EDVLPESLPL GIRQRLSLAV
AVIHRPEMLI LDEPTSGVDP VARDMFWQLM VDLSRQDKVT IFISTHFMNE AERCDRISLM
HAGKVLASGT PQELVEKRGA ASLEEAFIAY LQEAAGQSNE AEAPPVIHDT THAPRQGFSL
RRLFSYSRRE ALELRRDPVR STLALMGTVI LMLIMGYGIS MDVENLRFAV LDRDQTVSSQ
AWTLNLSGSR YFIEQPPLTS YDELDRRMRA GDITVAIEIP PNFGRDIARG TPVELGVWID
GAMPSRAETV KGYVQAMHQS WLQDVASRQS TPASQSGLMN IETRYRYNPD VKSLPAIVPA
VIPLLLMMIP SMLSALSVVR EKELGSIINL YVTPTTRSEF LLGKQLPYIV LGMLNFFLLC
GLSVFVFGVP HKGSFLTLTL AVLLYIIIAT GMGLLISTFM KSQIAAIFGT AIITLIPATQ
FSGMIDPVAS LEGPGRWIGE VYPTSHFLTI ARGTFSKALD LTDLWQLFIP LLIAIPLVMG
LSILLLKKQE G
//
