ID   E1NMX4_9LACO            Unreviewed;       428 AA.
AC   E1NMX4;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=UvrD/REP helicase {ECO:0000313|EMBL:EFO69539.1};
DE            EC=3.6.1.- {ECO:0000313|EMBL:EFO69539.1};
GN   ORFNames=HMPREF9212_1183 {ECO:0000313|EMBL:EFO69539.1};
OS   Lactobacillus iners LactinV 03V1-b.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=879298 {ECO:0000313|EMBL:EFO69539.1, ECO:0000313|Proteomes:UP000005160};
RN   [1] {ECO:0000313|EMBL:EFO69539.1, ECO:0000313|Proteomes:UP000005160}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LactinV 03V1-b {ECO:0000313|EMBL:EFO69539.1,
RC   ECO:0000313|Proteomes:UP000005160};
RA   Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFO69539.1}.
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DR   EMBL; AEHP01000022; EFO69539.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1NMX4; -.
DR   Proteomes; UP000005160; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF48; ATP-DEPENDENT HELICASE_NUCLEASE SUBUNIT A; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          2..428
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         23..30
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   428 AA;  50171 MW;  5E6AAF6C7B74C841 CRC64;
     MTSFTKEQEK AIYDSNIDIL VSASAGSGKT TVLVERVIEK ILHHQSIENL LIITFTKAAA
     SEMKLRIKNA IKNKIKEQPD NLFLKQQLAK VDIANISTID SFCLEVIRKF YYVINLDPNF
     SIMTDDTQLS LLKEKALLNT EKYFFENKDQ EFIDFYNNFA GDREVEAARS MLLELYYVTL
     AQPNYEAFLK RLDFFYQIDI NKNDIISSNL WQEKIKPLLL TNLQNIINKI SQYITEAEHN
     FSDLNKLIEQ LNLFMKSLNY LLAGIEQNLN YDEIRSRFSN CNFVGRLRRS SNWDESSTNL
     YQEISEFKAK CQDQLKKLFA SFFITDEKEQ LELLAKAQKL VKTISKVELT FINEFGKLKR
     KNNIIDFNDM EQFAYKILTS NSNNSDLARS YYQNKFSEIL VDEYQDVNEL QEQIIQVIKE
     KGKTIYLW
//