ID E1Q607_HELPP Unreviewed; 284 AA.
AC E1Q607;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN OrderedLocusNames=HPPC_02550 {ECO:0000313|EMBL:ADO06750.1};
OS Helicobacter pylori (strain PeCan4).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=765963 {ECO:0000313|EMBL:ADO06750.1, ECO:0000313|Proteomes:UP000006863};
RN [1] {ECO:0000313|Proteomes:UP000006863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PeCan4 {ECO:0000313|Proteomes:UP000006863};
RA Kersulyte D., Vasquez J., Gilman R.H., Berg D.E.;
RT "Complete genome sequence of Helicobacter pylori strain PeCan4.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
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DR EMBL; CP002074; ADO06750.1; -; Genomic_DNA.
DR RefSeq; WP_000471706.1; NC_014555.1.
DR AlphaFoldDB; E1Q607; -.
DR KEGG; hpc:HPPC_02550; -.
DR HOGENOM; CLU_091654_0_0_7; -.
DR Proteomes; UP000006863; Chromosome.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR006597; Sel1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR11102:SF147; FIBRONECTIN TYPE-II DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11102; SEL-1-LIKE PROTEIN; 1.
DR Pfam; PF08238; Sel1; 3.
DR SMART; SM00671; SEL1; 3.
DR SUPFAM; SSF81901; HCP-like; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}.
SQ SEQUENCE 284 AA; 32466 MW; BD45D88E9E876C11 CRC64;
MFKDFYRTTL SFLKPLLLLL VLLLPFSLCI ADEYISISDD WDERARNQWD EIARNHKTYY
FENGLDHFNQ GQYKQASKDF KLAQEYGIGL GNVYLAKMYL EGKGVKVDYK KAQFYAENAI
KGYGSGLLGG ALILGRMQAQ GLGMKKDLKQ ALKTYRHVVR IFSNKSTNYF ANNFRLPNLA
FTSMLIGSRF IDLSGLSANP IKFGKKFGIL VKKSTQIKDK TLSWEDIAEI SSNIILLKQQ
MGEILYRIGI AYKEGLGTRK KKDRAKKFLQ KSAEFGYEKA MEAL
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