ID E1QH57_DESB2 Unreviewed; 460 AA.
AC E1QH57;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:ADK84900.1};
GN OrderedLocusNames=Deba_1532 {ECO:0000313|EMBL:ADK84900.1};
OS Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802
OS / 2st14).
OC Bacteria; Thermodesulfobacteriota; Desulfarculia; Desulfarculales;
OC Desulfarculaceae; Desulfarculus.
OX NCBI_TaxID=644282 {ECO:0000313|EMBL:ADK84900.1, ECO:0000313|Proteomes:UP000009047};
RN [1] {ECO:0000313|EMBL:ADK84900.1, ECO:0000313|Proteomes:UP000009047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802 / 2st14
RC {ECO:0000313|Proteomes:UP000009047};
RX PubMed=21304732; DOI=10.4056/sigs.1243258;
RA Sun H., Spring S., Lapidus A., Davenport K., Del Rio T.G., Tice H.,
RA Nolan M., Copeland A., Cheng J.F., Lucas S., Tapia R., Goodwin L.,
RA Pitluck S., Ivanova N., Pagani I., Mavromatis K., Ovchinnikova G., Pati A.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C.,
RA Han C., Rohde M., Brambilla E., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Land M.;
RT "Complete genome sequence of Desulfarculus baarsii type strain (2st14).";
RL Stand. Genomic Sci. 3:276-284(2010).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP002085; ADK84900.1; -; Genomic_DNA.
DR RefSeq; WP_013258353.1; NC_014365.1.
DR AlphaFoldDB; E1QH57; -.
DR STRING; 644282.Deba_1532; -.
DR KEGG; dbr:Deba_1532; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_1_0_7; -.
DR OrthoDB; 9803618at2; -.
DR Proteomes; UP000009047; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000009047}.
FT DOMAIN 22..80
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 110..218
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 226..457
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 460 AA; 48203 MW; 97F4F02E6100A09F CRC64;
MSLELDVTPA LEAALGGGGE MAEAFLEDSS SLMVVIDNAK VEKVLGGQDL GVGLRLIKDL
RTSYAFGNQL RAQALVALAS DIAAERDAAP GRLHSFAPIA PGLAPAIVKP PIGVETARKV
EMARTAEAAA RAVDNRVRQV RVIYLERTQR VRVVNSLGVD ARDERTQVLM AIHCVAAEGA
VLQTGYESIG GLCGLELFDD QPPEQAARRA ARQAVMMLAA QPAPGGSMAV VLHSAAGGTM
IHEAVGHGLE ADIVLEGMSV YKDQVGRQVA SPLITVIDDG SLAGKRGSAG FDDEGVPTGR
NVLIAGGVLK GYLHDRLSAM KMNARPTGNG RRENYRQRPI PRMTNTFIAP GHDDPEAIIA
DTPHGLLVKK MGGGQVNTTN GDFVFEVAEG YLIENGRVGR PVRGATLTGN GPKVLMDIDR
VANDLGFGIG TCGKEGQGSP VADAQPTLRI PSIVVGGRQG
//
