ID   E1U3N2_9CYAN            Unreviewed;      2389 AA.
AC   E1U3N2;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Non-ribosomal peptide synthetase module-related protein {ECO:0000313|EMBL:ACN96039.1};
OS   Fischerella sp. MV11.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae;
OC   Fischerella.
OX   NCBI_TaxID=397321 {ECO:0000313|EMBL:ACN96039.1};
RN   [1] {ECO:0000313|EMBL:ACN96039.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MV11 {ECO:0000313|EMBL:ACN96039.1};
RA   Hess W.R., Scholz I.D.;
RT   "High diversity of cyanobacterial nonribosomal peptide synthetase genes in
RT   isolates from geothermal sites and hot springs of Costa Rica.";
RL   Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
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DR   EMBL; FJ211387; ACN96039.1; -; Genomic_DNA.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR   GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR   CDD; cd12114; A_NRPS_TlmIV_like; 1.
DR   CDD; cd19535; Cyc_NRPS; 2.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 4.
DR   Gene3D; 1.10.1200.10; ACP-like; 2.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR   Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR041464; TubC_N.
DR   InterPro; IPR044894; TubC_N_sf.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   PANTHER; PTHR45527:SF10; PHENYLOXAZOLINE SYNTHASE MBTB; 1.
DR   Pfam; PF00501; AMP-binding; 2.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 2.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   Pfam; PF00550; PP-binding; 2.
DR   Pfam; PF18563; TubC_N; 1.
DR   SMART; SM00823; PKS_PP; 2.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR   SUPFAM; SSF47336; ACP-like; 2.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00455; AMP_BINDING; 2.
DR   PROSITE; PS50075; CARRIER; 2.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1238..1313
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          2312..2387
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   2389 AA;  270519 MW;  F63098B2ABEB6A91 CRC64;
     MATDILQKFK EQGIELWAEG DKLRFRATKG VLTPSLREEL VNHKEAILRS LFWTGISSIS
     DISQITPASQ ERYQPFPLTE IQQAYLLGRS EIFSLSGVSA HAYQEFEAAN INIKQLNQSL
     NRVIAHHDML RAIVLPSGEQ KILEQVPEYE IKFLDLRGKS LQEVDSCLEK IRSEMSHQVL
     PTDKWPLFEI RATQINEEIT LIHLSTDLLI CDAYSNQLLI QEWFQVYHQP DIQLVGTEFS
     FRDYVLALAS LQDSQLYQRS QAYWQKRLST LPLAPDLPLV KQVSSITKPR FVRREGKLDS
     ETWRKLKHKA TQLHITGSGL LCAAFSEVLA VWNPNPHFTL NLTLFNRLPL HPEVEQILGD
     FTTTILLEVN QSLNTFTTRA QRLQQQIWED LEYSQISGVQ VLRELAKQQG RSSSGILMPV
     VFSSALFSEA TQPQETATIP WKEVYGITQT PQVLLDHQVR EDTGALIFNW DSVDEVFPPG
     MLDDMFAAYY QLLELLACDD SAWQQPTRQL VPQTQLEQQA VENATAAPIS RELLHTLFAT
     QVKAQRYSKA IVSHKRTMTY EELSDHAHQI GHQLRQLSVR PNQLVAVVME KGWEQIVAVL
     GILNSGAAYL PIDPSLPTER QRYLLENGKV QVVLTQSWLS ESLEWPENIQ PICVDTQVID
     NTVVPLEPIQ QPEDLAYVIY TSGSTGLPKG VMIDHRGAVN TIIDINKRFG IGSEDKILAL
     SALNFDLSVY DIFGTLAAGG TIVIPEPART KDPAHWIELV DKAVVNVASQ KLVAYVVPNL
     NNCPSLFAVK TGDAEKFITT WASLVQAGRQ QALQLPLEMN LQLYGTFWQS LEDFCTLSMC
     CTLTKLGVFI QPREKHSLEE LVRTCGIDEK QKWLLGHWLK VLQQEGLLEE VATETFMNFQ
     PLPSDFWNDL WQEIERSATW GNQAQTWQEY VKCSIDNHPA LLRGEIDLRE LLFPDGSWKT
     AESLYALNPF TDYHNSIAQE ILRVVVGDWN QDRPLQILEV GAGTGGTTAA LLPVLLLCQA
     VYTYTDISQF FTNQAQDKFK NYSFIEYGIL DVDKNPVHQG YEPHSFDVIV AANVIHNARN
     VDKTLEYLRS LLTPNGILLL LEVTKNSRTQ MVTVGFIEQF THLEDERKKT KMPLLSVAEW
     GKALDQAGFE EFVAFPESKS STEALEQHLI VAKAPAHVRS FQPSVLHTYL HNKLPEYMLP
     SAYVLLETLP LSTNGKIDRK ALPEFNLVKS QQEKTFVLPR TSLEKQLVEI WADILNIKQI
     GIHDNFFEIG GDSLLAIQVS SRVRQAFCVE LPLRRLLDSP TIAGLAKYIQ IARQEQQTEN
     ETVVENLPSV VPQLNMRFEP FSLTDIQQAY WVGRMGAFEL GNVSTHIYLE LLSRGLDLER
     LNLALQKLIE RHDMLRAIIL PDGQQQVLEK VPLYQIEILD LSRENEEAIA AGIDRVRQEM
     SHKVRPANQW PLFEFRVTLL NAGHVRLHVS IDAIILDGYS ILTLFKEWSQ LYEHPELALP
     PLEISFRNYI QAEQALRNTE LYRRSQDYWF NRLDTLPKAP ELPLAQKPHQ QQLFKRRVSE
     LDKTLWQQLN QRAAKAGITA SGVLIAAFAE ILTVWSKSPD FTINLTLFNR LPLHPQVNNL
     IGDFTSLNLL EVHNDTNESF STRATRIQKQ LWQDLEHRYV TGVEVLREMS RRQGGARVTM
     PVVFTSALVL GSLGEDASVL NHFGDLGYSV SQTPQVWLDH QVINKNGALV LIWDAVEELF
     PEGLLDEMYE SYCNFLKRLA TSDQEWIKPI RQLVPTTNLE LQAAVNATAA PVAEELLHTM
     FLRQVQVRTH SPAVITSQQS FTYQELFTRA NSVGHRLRKL GVSPNQLVAV VMEKGWEQIV
     AVLGILMSGA AYLPIDPELP TERRLYLLTQ GEAVCILTQS HLNQDLEWPN SIPRLCLDDS
     DDLLAVDKSP LHSVQSPEDL AYVIYTSGST GLPKGVMIDH RGAVNTITDI NQRFGIGSDD
     KILALSSLNF DLSVYDIFGT LAAGGTIVIP DASARKYPAH WLELMQREQV TVWNSIPTLM
     QMLVEYAGGC QETLPISLRL VMLSGDWIPL NLPNLIKAAA NQTQIVSLGG ATEASIWSIC
     YPIETVDRHW KSIPYGKPLQ NQRLYVLKES LEPCPVWAVG QLYIGGIGLA QGYWHDEQKT
     NSSFIIHPHT GERLYQTGDL GRYLPDGNIE FLGRVDSQVK IRGHRIELGE VESTLAQHPA
     IRSVAVVAVG DDEKSKDYLV AYVVPDREQT VTEEQLIVNL RTFLKQKLPE YMIPSAFLTL
     ETLPLNPNGK VDRKALVKQT YFQPEPEVVY VAPQNEVERI IAKVFQELMQ VENVGLYDNF
     FHLGANSLHL VRLHSKLQEI FHQDFAIATL FQSPTIYALA QHFNAYHAE
//