ID   E1WVM1_BACF6            Unreviewed;       954 AA.
AC   E1WVM1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Putative peptidase {ECO:0000313|EMBL:CBW23930.1};
GN   OrderedLocusNames=BF638R_3469 {ECO:0000313|EMBL:CBW23930.1};
OS   Bacteroides fragilis (strain 638R).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=862962 {ECO:0000313|EMBL:CBW23930.1, ECO:0000313|Proteomes:UP000008560};
RN   [1] {ECO:0000313|EMBL:CBW23930.1, ECO:0000313|Proteomes:UP000008560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638R {ECO:0000313|EMBL:CBW23930.1,
RC   ECO:0000313|Proteomes:UP000008560};
RX   PubMed=20829291; DOI=10.1099/mic.0.042978-0;
RA   Patrick S., Blakely G.W., Houston S., Moore J., Abratt V.R., Bertalan M.,
RA   Cerdeno-Tarraga A.M., Quail M.A., Corton N., Corton C., Bignell A.,
RA   Barron A., Clark L., Bentley S.D., Parkhill J.;
RT   "Twenty-eight divergent polysaccharide loci specifying within- and amongst-
RT   strain capsule diversity in three strains of Bacteroides fragilis.";
RL   Microbiology 156:3255-3269(2010).
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261}.
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DR   EMBL; FQ312004; CBW23930.1; -; Genomic_DNA.
DR   RefSeq; WP_005817299.1; NC_016776.1.
DR   AlphaFoldDB; E1WVM1; -.
DR   KEGG; bfg:BF638R_3469; -.
DR   PATRIC; fig|862962.3.peg.3594; -.
DR   HOGENOM; CLU_008156_0_0_10; -.
DR   Proteomes; UP000008560; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..954
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003154414"
FT   DOMAIN          51..179
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          206..380
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          696..875
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   954 AA;  109462 MW;  808F5EE7DD3A58EC CRC64;
     MKRNNKNRYL YIAAIFIAAM LPYTACPQST PILLPPGTVE GRLPNGLHYL ILHNASPASR
     VEFRLIMRVG SVQETEQEKG CAHFLEHITF GGTRHFPKRS LVEYLESLGM KYGQDINAFT
     GFDRTIYMFA VPTDFAKDEA LDRSLLILHD WLDGVTIDPE KVENEKGIIL EELRGFDPED
     DFYPLKIGQG IFSHRMPLGT TDDIRKVTPQ VLKNYYHKWY VPSLATLVIV GDISPLEIES
     KIKERFKSLP GRPVNDFRNY PLEYTRGIHL ASIRDSLQPR TKVELMIPHP CTVERTMEDA
     IAKEKGRLLV SAISSRFRAR KLKTDVTDQW YLSDKNHFVL TVEGENRKEI LTSISTTVSL
     LNDLIRNGWQ EDELQDIKNN FCRRMKLSTD APSRPSSMWC DDFADYVISG DRYLTDPSQQ
     QQLKEAMSRV SGQSLQTLLK EWMSYREETL LVACSTHPGL GAPLSETEIA SAWAQGEQVE
     CTPFLYFRPE KQEEIDIETP PCLAARFPFD PASVLRQTEY PQNRIREVEL KNGIRLVLKP
     TLEADSTLLI TSFAPFGTSS LSDEEYPLLE GFAGYIDMGD IAKVDGQVLS DYLFRKEISL
     SMAVENHWHG FIGMSPTANA PELFNLIYEK IFDPELKYDE FEEIRQDLLE NQDKETILEK
     MLQRSPDRLL SARINELTGT GFARSSQKLS SEQIKNLNLD SIAAFYKKLY TNPQGTTYVI
     CGNFNADTLM QQFVSVFGRI PVSSHLSRFS YPHFNFPVRK HIEGFPNDND TQTLFDYLLP
     GHYQPGLKNT LTLKLMRDLI RNRLISVLRE QKSLVYSPYI SLMYEGIPQG IFYFDINASA
     DNDNMPQIEQ LLKEILHQLK QQEVDNEELN TLKRSFLIAK REALNEESPS AWRTALVGLL
     KNGETISDFD HYEQCLDSIT PAMLREAFRR YLDTENYILL YLSKNKLKND TSNH
//