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Database: UniProt
Entry: E1WZQ5_HALMS
LinkDB: E1WZQ5_HALMS
Original site: E1WZQ5_HALMS 
ID   E1WZQ5_HALMS            Unreviewed;       392 AA.
AC   E1WZQ5;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   05-JUL-2017, entry version 50.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   OrderedLocusNames=BMS_1376 {ECO:0000313|EMBL:CBW26241.1};
OS   Halobacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ)
OS   (Bacteriovorax marinus).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Bdellovibrionales;
OC   Halobacteriovoraceae; Halobacteriovorax.
OX   NCBI_TaxID=862908 {ECO:0000313|EMBL:CBW26241.1, ECO:0000313|Proteomes:UP000008963};
RN   [1] {ECO:0000313|Proteomes:UP000008963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-682 / DSM 15412 / SJ
RC   {ECO:0000313|Proteomes:UP000008963};
RX   PubMed=22955231; DOI=10.1038/ismej.2012.90;
RA   Crossman L.C., Chen H., Cerdeno-Tarraga A.M., Brooks K., Quail M.A.,
RA   Pineiro S.A., Hobley L., Sockett R.E., Bentley S.D., Parkhill J.,
RA   Williams H.N., Stine O.C.;
RT   "A small predatory core genome in the divergent marine Bacteriovorax
RT   marinus SJ and the terrestrial Bdellovibrio bacteriovorus.";
RL   ISME J. 7:148-160(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; FQ312005; CBW26241.1; -; Genomic_DNA.
DR   STRING; 862908.BMS_1376; -.
DR   EnsemblBacteria; CBW26241; CBW26241; BMS_1376.
DR   KEGG; bmx:BMS_1376; -.
DR   PATRIC; fig|862908.3.peg.1308; -.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OrthoDB; POG091H2ZWF; -.
DR   BioCyc; BMAR862908:GJBX-1312-MONOMER; -.
DR   Proteomes; UP000008963; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008963};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008963}.
FT   DOMAIN      306    374       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   392 AA;  44839 MW;  FEAA81DBFA06D71E CRC64;
     MFMQNKKGSP RATAINKKLV RNRAQDESQL DLLSYISNQN IAVSRPSNIT CISSAKRPKA
     ITRNRKFSLP INVDRNKVFK NFICGESNSR AYKVMESTLN SKNIDYQIIY ICSLSGLGKS
     HLLYATANAL FEKTAKKICY FHGKEFIYNF DAQVENLDSI AAVFVDDLDE ITYDIDLQDR
     FSRNFDLLKR SGVQIFLAGS ILPKHMKMAN AKYANRVGGA LVEKINKIDR DLASKILDNL
     STIHNYQLSP DVSDLLVDCF HYHVYGLESA LLKLKSYSET FSSNVDIKIA LKELKILGPV
     LDKNINSKKI ICRVCEFYKV DVEDLFSKNR KKEVSFARHV CMYILKDRNG LSLSRIARLF
     NRDHTSVLYG VNKVMAEIQN NKKFRKDIHE LV
//
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