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Database: UniProt
Entry: E2AGR1_CAMFO
LinkDB: E2AGR1_CAMFO
Original site: E2AGR1_CAMFO 
ID   E2AGR1_CAMFO            Unreviewed;      3132 AA.
AC   E2AGR1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   07-JUN-2017, entry version 33.
DE   SubName: Full=Ryanodine receptor 44F {ECO:0000313|EMBL:EFN67324.1};
GN   ORFNames=EAG_04785 {ECO:0000313|EMBL:EFN67324.1};
OS   Camponotus floridanus (Florida carpenter ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Aculeata;
OC   Vespoidea; Formicidae; Formicinae; Camponotus.
OX   NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN   [1] {ECO:0000313|EMBL:EFN67324.1, ECO:0000313|Proteomes:UP000000311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
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DR   EMBL; GL439408; EFN67324.1; -; Genomic_DNA.
DR   InParanoid; E2AGR1; -.
DR   OMA; QNANTDM; -.
DR   Proteomes; UP000000311; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000311};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:EFN67324.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2459   2483       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2653   2676       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2739   2761       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2871   2892       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2930   2950       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   3004   3027       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      235    467       RYDR_ITPR. {ECO:0000259|Pfam:PF01365}.
FT   DOMAIN      845    934       RyR. {ECO:0000259|Pfam:PF02026}.
FT   DOMAIN      964   1047       RyR. {ECO:0000259|Pfam:PF02026}.
FT   DOMAIN     2008   2123       RIH_assoc. {ECO:0000259|Pfam:PF08454}.
FT   DOMAIN     2498   2767       RR_TM4-6. {ECO:0000259|Pfam:PF06459}.
FT   DOMAIN     2894   3036       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   3132 AA;  355967 MW;  AA7F2EA962E70A09 CRC64;
     MAEGAKLQMC YLLHHLNDIQ LRHRVESIIS FAYDFVGELQ TDQLRRYIDI KQSDLPSAVA
     AKKTREYRCP PREQMNAILS FKNLDEEDPE NWPCGEELIG KMNEFHSELM SYVSLNALQE
     AANAADEPAE EVQKPGAMKR LFNFINAVKE LEEEPKPEPE PVKKTPEEVF RKVLISTIVS
     WAEESQIETP KLVREMFSLL VRQYDTVGEL IRALEKTYVV NNKTKDDVAL MWVGLSQIRA
     LLPVQMSQEE EALVRERLWK LVNNHTFFQH PDLIRVLRIH ENVMAIMMNT LGRRAQAQSD
     AQTQAQATEG EPTSKEKDTS HEMVVACCRF LCYFCRTSRQ NQKAMFDHFD FLLENSNILL
     ARPSLRGSTP LDVAYSSLME NTELALALRE HYLEKIAIYL SRCGLQSNSE LVEKGYPDLG
     WDPVEGERYL DFLRFCVWVN GESVEENANL IIRLLIRRPE CLGPALRGEG EGLLRAIIEA
     NKMSERIADR RKVHDEAEGT AMMMQFEHPL PESDDDEDYI DTGAAILNFY CTLVDLLGRC
     APDSSVIEQG KNESLRARAI LRSLVPLDDL QGVLSLRFTL LNPAAGEERP KSDMPSGLIP
     GHKQSVVLFL ECVYGIETQE LFYKILEEAF LPDLRAATML DRNDGYESDM ALAMNRYIGN
     SILPLLIKHS KFYNEADNYA SLLDATLHTV YRLSKNRMLT KGQREAVSDF LVALTSQMQP
     SMLLKLLRKL TVDVSKLSEY TTVALRLLTL HYDRCAKYYG STGSGGQGTY GASSDEEKRL
     TMVLFSNIFD SLSKMDYDPE LFGKALPCLT AIGCALPPDY SLSKNYDDEW YGSKSASAQS
     PDGPYNPQPI NTSSVVLNND LNQIVQKFSE HYHDAWASRK LENGWTYGDQ WSDVNKTHPR
     LKPYNMLSDY ERERYKEPVR ESLKALLAIG WNIEHAEVDV PSTNRSSMRR SSKSQGDSAS
     PFNYNPHPVD MTNLTLSREM QNMAERLADN AHDIWAKKKK EELITCGGGI HPQLVPYDLL
     TDKEKRKDRE RSQEFLKYLQ YQGYKLHKPN RGGTETEVAG AAASVELRFA YSLLEKLIAY
     LDKATINMKL LKPSDTFSRR NSFKTSTRDI KFFSKVVLPL MEKYFSTHRN YFIAVATATN
     NVGAASLKEK EMVASLFCKL ASLLRSRLAA FGADVRITVR CLQVLVKGID AKSLVKNCPE
     FIRTSMLTFF NNTADDLGHT ILNLQEGKYS HLRGTHLKTS TSLSYINSVV LPVLTAMFDH
     LAACEYGSDL LHASLTHERK YLKTEIDRHK PNLGSCLGAF SSCFPVAFLE PHLNKHNQYS
     LLNRIADHSL EAQDIMTKME SSMPTLETIL TEVDQFVESD KTYNDAPHIV DVILPLLCSY
     LPFWWAQGPD NVNPTEGTYV SMITSDHMNQ LLKNVLKLIK KNIGNENAPW MTRIAAYTQQ
     IIINSSEELL KDPFLPLAER VRKRTDTMFH KEESLRGFIK SSTDDTSQVE AQIQEDWQLL
     VRDIYSFYPL LIKYVDLQRN HWLRNNISEA EDLYNHVAAI FNIWSKSQYF LREEQNFISA
     NEIDNMVLIM PTATRRPAAV SDGSAPSGGS KKKKKHRDKK RDKDKEVQAS LMVACLKRLL
     PVGLNLFAGR EQELVQHCKD RFLKKMQEQE IAEFAKTQLT LPDKIDPADE MSWQHYLYSK
     LGQKKDALEP STKAQQLEDV VARITDMAKV LFGLHMIDHP QQQSKSQYRS VVSIQRKRAA
     TKPPPSRDGW KRVLCAARKR AAIACLRSEP LYKLRRHRAI NIFARTYYET WLQEENVGQE
     VMIEDLTQSF EDAELNKTES EDEGKPDPLT QLVTTFCRGA MTERSGALQE DPLYMSYAHI
     ISKSCGEEEE EGEEEGDGGG GSEEEGGASI HEQEMEKQKL LFHQARLANR GVAEMVLLHI
     SACKGVPSDM VIKTLELGIS ILRGGNIEIQ RGMLNHLKEK KDVGFFTSIA GLMNSCSVLD
     LDAFERNTKA EGLGVGSEGA AGEKNMHDAE FTCALFRFIQ LTCEGHNLDW QNYLRTQAGN
     TTTVNVVICT VDYLLRLQES IMDFYWHYSS KELIDPAGKA NFFKAIGVAS QVFNTLTEVI
     QGPCAQNQQA LAHSRLWDAV GGFLFLFSHM QDKLSKHSSQ VDLLKELLNL QKDMITMMLS
     MLEGNVVNGT IGKQMVDTLV ESASNVELIL KYFDMFLKLK DLVSSPSFLE VDFNNDGWVY
     PKDFKEKMEQ QKSYTNEEIE FLLACCETNH DGKIDYVAFM DRFHEPAKEI GFNLAVLLTN
     LSEHMPNEPR LARFLETAGS VLNYFEPFLG RIEILGGNKK IERVYFEIKE SNIEQWEKPQ
     IKESKRIYFY NTVVEAGEKE KLETFINFCE DAIFEMQHAS ALMTVEESGG IGKARESSYT
     YLTEDDEERN KDPIRRGIQA FKDGIYYCFY LFSPTNIKNK IAEMQQMTIP ELFIGFFKMI
     FYAFYYSGFG IGCVIKYFMG LLLTLMRGPR LEEPVAIKEE EEKPSRLLPA LPPTPDESNL
     QVQAFGMDIT KEEGGQIRIA PHESSTSTPQ SSIEETGEST PDEGTGEEGA TAEGGESEAP
     VTLADLLGGE QARAQAAAAA EAAAAQQAAM AAVEAEAKQE PSVEPSTGSS IDLSDYSHRV
     VSFLARNFYN LKYVALALAF CINFMLLFYK VSFLAVDLNE EGSGRIADIL AEMSGDGPSG
     LAGSGVEMGS GSGESDDSEE EDEDDQEFVE MDYYYMAHVM RLLAALHSLV SLAMLVAYYH
     LKVPLAIFKR EKEIARRVEF DGLYIAETPE EDDIKAHWDK MVISAKTFPV NYWDKFVKKK
     VRQKYSETYD FDYISNLLGM EKTSFSQQEE EGSGLIHFII TIDWRYQIWK AGVTITDNAF
     LYSLWYFVFS ILGNYNNFFF AAHLLDVAVA VKTLRTILQS VTHNGKQLVL TVMLLTIVVY
     IYTVIAFNFF RKFYIQEEDD ETDKKCHHML TCFVFHLYKG VRAGGGIGDE IGEPDGDDYE
     VYRIMFDITF FFFVIVILLA IIQGLIIDAF GELRDQLDNV KTNMESNCFI CGLGKEYFDA
     VPHGFDTHVQ QEHNLANYMF FLMHLINKPD TEYTGQETYV WNMYQQRCWD FFPVGDCFRK
     QNETVEEEAK KK
//
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