ID E2ASE9_CAMFO Unreviewed; 630 AA.
AC E2ASE9;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Glucose dehydrogenase [acceptor] {ECO:0000313|EMBL:EFN63615.1};
GN ORFNames=EAG_07393 {ECO:0000313|EMBL:EFN63615.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN63615.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; GL442298; EFN63615.1; -; Genomic_DNA.
DR RefSeq; XP_011263210.1; XM_011264908.2.
DR AlphaFoldDB; E2ASE9; -.
DR STRING; 104421.E2ASE9; -.
DR InParanoid; E2ASE9; -.
DR OMA; NYPWIHI; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF215; FI02019P; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2, ECO:0000256|RuleBase:RU003968};
KW Flavoprotein {ECO:0000256|RuleBase:RU003968};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 136..159
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 312..326
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 138
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 275
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 630 AA; 70118 MW; 6B5E1AFE1190A7FD CRC64;
MVFSTIIVTS ALKGAISLMG TGLWLVPLLI AGLSYYHYDQ LDPESRPIDR YPLYSNYDFI
VVGGGSAGAV VASRLSEIPD WNVLLLEAGP DENEITDVPS LAAYLQLTKL DWKYKTEPTG
KACLAMKGGR CNWPRGKVLG GSSVLNYMLY VRGNRYDYDH WESLGNSGWG YKQVLYYFKK
SEDNRNPYLQ KSPYHATNGY LTVQESPWKT PLVVAFIQAG VEMGYENRDI NGERQTGFMI
SQGTIRRGNR CSTAKAFLRP VRLRRNIHTA INSHVTKIII DPLTMKAIGV EFVRDGRKQM
VRARKEVILS AGAINSPQIL MLSGIGPKEH LRHIGIPVIE DLRVGDNLQD DVGMGGLAFL
IDKPVVIVQD RFQSAPMTMH YVVNGRGPMT ALGGVEGYAF VNTKYANYSI DYPDLQFHMA
PASINSDAGV QVRKIFGLTD EVYNTVYRPI TNKDAWTLIP VLLRPKSRGT IRLKNSNPFH
SPLINANYFS DPMDIAVLVE GVKIAIKISE AKVFKQFGSR IHRIKLPGCK HFKFGSDAYW
ECHIRHISET IYHPVGTAKM GPPTDPTAVV DPRLRVYGIT GLRVIDASIM PTISSGNTNA
PVIMIGEKGA DLIKQDWLRS SSGNNHESVY
//
