ID E2B307_HARSA Unreviewed; 1070 AA.
AC E2B307;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Diacylglycerol kinase delta {ECO:0000313|EMBL:EFN89976.1};
GN ORFNames=EAI_15275 {ECO:0000313|EMBL:EFN89976.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN89976.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN89976.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL445250; EFN89976.1; -; Genomic_DNA.
DR AlphaFoldDB; E2B307; -.
DR STRING; 610380.E2B307; -.
DR InParanoid; E2B307; -.
DR OMA; SANRECN; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20800; C1_DGK_typeII_rpt1; 1.
DR CDD; cd20852; C1_DGK_typeII_rpt2; 1.
DR Gene3D; 3.30.60.20; -; 2.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF34; DIACYLGLYCEROL KINASE ETA; 1.
DR Pfam; PF00130; C1_1; 2.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00109; C1; 2.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 2.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 2.
DR PROSITE; PS50081; ZF_DAG_PE_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EFN89976.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1..13
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 29..79
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 102..153
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 183..320
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT REGION 489..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 636..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..770
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1070 AA; 117058 MW; 7D9E5C1024B2BD1B CRC64;
MEEWLQALRT TTESRSQVDP GTAELLGGNH QWYATSHARP TYCNVCRDAL HGVTSHGLSC
EVCKYKVHKR CSAKAINNCK WTTLASIGKD IIEDQDGNIT MPHQWMEGNL PVSSKCLVCE
KTCGSVLRLQ DWRCLWCRAT VHTACRPAIS IRCPLGPAKL SVVPPTALHS IGSDEAWEAV
RPTGCSPLLV FVNSKSGDNQ GVKFLRRFKQ LLNPAQVFDL IKGGPGPGLR LFRHFDPFRI
LVCSGDGSVG WVLSEIDRLG MHKQCQVGVL PLGTGNDLAR VLGWGASCDD DTHLPQLLEK
YEKAGTKMLD RWSVMTFERS ISLPCHKVTL HQPDPAIKLS VAHQYEDSVL AHITNILQSD
QDNVVISSAK VLCETVKDFA THILEASLNT GDQQLGEKCE ILQQKLDLLL QTLSEEESYL
SDNGEETDVG TVRTNTLSSD QEKGALEKPE KEMTNLKRVQ RRKCYMEKDA VMSRANSLKR
AIRRLVEHTE TAVDEQNNPS DEKQGSKMPN ITVTSDISPI NSTGKKQQLD IPGFQTDQID
NFNLMPTIDS ASSVDISPCP SPTPNVASLS PMPDLRRDSQ PEELLTLPAP DGFADSRRNS
ENIMQGAFTF DEPAAQIAGG QSGMQAAVSD NLLTSEPTQV EASSDIPVTV TRTTLDTSTP
SDDATMQDTI VSPDTDSLHS RNISPEPQAQ KLSQSKLEPR GSCTNSIVST DSIVSDTLDS
RSCTIRNSES EIGHIDSDIF DSSKKSDSSE IGHIDSPDNS DMFSSETQHS ESVIDDLSSL
GQDLISTILA ERYDSVRECL ESEEIEKPQK FCSLAQFVEG NDIARQSFKK GPKNMKTDRE
VNIEGMLNKY KTDGLATCVR VTGNKSMHPV ETNVIPAPNR FPSVEKEKTS DLLSPVCCFT
VSSDNTPANE KYATNFPPTI SVIIDPPSPS MSIESHQELN LDYKLDPHIK QYSGSSMERL
SVELPESGFS PQATRRISSG SLLKASEVVS LAATTARLGG SSVSLRNERA KSMDKTEDVK
KLPIINPLVR LPMWPNVSGG AGLISQALLA NADALCAAVS PLMDPDESLM
//
