ID E2BDL4_HARSA Unreviewed; 816 AA.
AC E2BDL4;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000256|ARBA:ARBA00018774};
DE AltName: Full=U5 snRNP-specific protein, 116 kDa {ECO:0000256|ARBA:ARBA00031432};
GN ORFNames=EAI_11264 {ECO:0000313|EMBL:EFN86176.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN86176.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN86176.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GL447678; EFN86176.1; -; Genomic_DNA.
DR AlphaFoldDB; E2BDL4; -.
DR STRING; 610380.E2BDL4; -.
DR EnsemblMetazoa; XM_011138525.3; XP_011136827.1; LOC105181631.
DR InParanoid; E2BDL4; -.
DR OMA; YIFRPIR; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022728};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00022728};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Ribonucleoprotein {ECO:0000313|EMBL:EFN86176.1};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 547..668
FT /note="Translation elongation factor EFG/EF2"
FT /evidence="ECO:0000259|SMART:SM00889"
FT DOMAIN 670..759
FT /note="Elongation factor EFG"
FT /evidence="ECO:0000259|SMART:SM00838"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..49
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 92269 MW; DA77836C42A5FDD2 CRC64;
MDADLYDEFG NYIGPDLASE SEDENEYGNV GDDTEDRERS DEEMEEDKDE SREHADQGSS
MAVVLHEDKR YYPSALEVYG PEVETLVQEE DAQPLDKPLI APTRKPKFQI KQQQLPDTTY
SIEFLADMMD APHLIRNVVL LGHLHHGKTT LVDCLVRQTH PYLHSVTDEK PLRSHPGLNA
NEFAKRLWGD IYFNPKTRKF TKKPPHNTAQ RSFIEFILEP LYKIFAQVVG DVDTTLPDVL
DELGIRLTSE EMKMNIRPLL RLVCTRFLGD MCGLVDMCIT HVPSPQSHAP TKVQHVYTGP
IESPLAQDMV NCDPDGRLMI HSTKMYPTED CTLFVVLGRV MSGTLEAGQR VRVLGEAYSR
TDEEDSRVLT VGRLWISEAR YSIELSRVPA GNWVLIEGID RPIVKTSTIT DLDNSEELHI
FRPLKFNTQS VIKIAVEPVN PSELPKMLDG LRKVNKSYPL LGTRVEESGE HVVLGTGELY
LDCAMHDLRR MYSEIDIKVA DPVVAFAETV VETSSLKCFA ETPNKRNKLT MIAEPLERGL
AEDIEAEHVR ITWNKKRLGE FFQTKYDWDL LAARSIWAFG PDSTGPNILV DDTLPSEVDK
TLLNSARDAI IQGFQWGTRE GPLCEEPIRN VKFKILDAVI AQEPLHRGGG QIIPTARRVA
YSAFLMATPR LMEPYLFVEV QAPADCVSAV YTVLAKRRGH VTQDAPVPGS PLYTIKAFIP
AIDSFGFETD LRTHTQGQAF CLSVFHHWQI VPGDPLDKSI TIRPLEPQPA THLAREFMLK
TRRRKGLSED VSINKFFDDP MLLELARQDV LLNYPL
//
