ID E2BI61_HARSA Unreviewed; 408 AA.
AC E2BI61;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE SubName: Full=WD repeat and FYVE domain-containing protein 2 {ECO:0000313|EMBL:EFN84632.1};
GN ORFNames=EAI_02934 {ECO:0000313|EMBL:EFN84632.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN84632.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN84632.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR EMBL; GL448450; EFN84632.1; -; Genomic_DNA.
DR RefSeq; XP_011139252.1; XM_011140950.2.
DR AlphaFoldDB; E2BI61; -.
DR STRING; 610380.E2BI61; -.
DR EnsemblMetazoa; XM_011140950.3; XP_011139252.1; LOC105183081.
DR GeneID; 105183081; -.
DR KEGG; hst:105183081; -.
DR InParanoid; E2BI61; -.
DR OMA; EIRCLRW; -.
DR OrthoDB; 5385125at2759; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15718; FYVE_WDFY1_like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR042234; WDFY1/WDFY2.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46189; LD41958P; 1.
DR PANTHER; PTHR46189:SF1; LD41958P; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 203..236
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 246..287
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 289..360
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
SQ SEQUENCE 408 AA; 46055 MW; DCF5B21C611A6A0A CRC64;
MAAEIKPAPG VNHDKFSNSR KPVLLSKLEG CSDDVNAAII IPREEGVISV CDDRTIRVWL
KRDSGHYWPS ICQYMPAGAT SMHYCIETRQ LFVGLDNGCI NEFILEQDYN RMTAMREYLA
HQARVTGIIF APDCEWILSI GRDKLFQIHS SETGQKLGSY QTDAWYTALQ FDAQSKHAFV
GDYSGQIAML KLDNNSITFI TTLKAHRGSI HTLAWDSEKQ LLFSGSFDRS IIVWDIGGRQ
GTAYELQGHH NKVTALCYAS AERVLLSGGE DGVIVCWNMA ANRKETAAWV ESDTCQACGR
PFFWNIKAMM DQRQLGLRQH HCRHCGRALC ARCTSQRIPI PAMGFEFEVR VCDQCHIQLK
SENQSSLASF HDAKHSVVGM DLDIVRRRLL TIGQDRVIKI WDISALFQ
//
