ID E2BVX5_HARSA Unreviewed; 296 AA.
AC E2BVX5;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Exosome complex exonuclease RRP4 {ECO:0000313|EMBL:EFN80153.1};
GN ORFNames=EAI_16782 {ECO:0000313|EMBL:EFN80153.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN80153.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN80153.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the RRP4 family.
CC {ECO:0000256|ARBA:ARBA00009155}.
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DR EMBL; GL451066; EFN80153.1; -; Genomic_DNA.
DR AlphaFoldDB; E2BVX5; -.
DR STRING; 610380.E2BVX5; -.
DR InParanoid; E2BVX5; -.
DR OMA; GVNGFIW; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd22525; KH-I_Rrp4_eukar; 1.
DR CDD; cd05789; S1_Rrp4; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR025721; Exosome_cplx_N_dom.
DR InterPro; IPR026699; Exosome_RNA_bind1/RRP40/RRP4.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR048565; RRP4_S1.
DR PANTHER; PTHR21321:SF4; EXOSOME COMPLEX COMPONENT RRP4; 1.
DR PANTHER; PTHR21321; PNAS-3 RELATED; 1.
DR Pfam; PF14382; ECR1_N; 1.
DR Pfam; PF15985; KH_6; 1.
DR Pfam; PF21266; RRP4_S1; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF110324; Ribosomal L27 protein-like; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000313|EMBL:EFN80153.1};
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Hydrolase {ECO:0000313|EMBL:EFN80153.1};
KW Nuclease {ECO:0000313|EMBL:EFN80153.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 30..68
FT /note="Exosome complex component N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14382"
FT DOMAIN 80..152
FT /note="RRP4 S1"
FT /evidence="ECO:0000259|Pfam:PF21266"
FT DOMAIN 174..214
FT /note="K Homology"
FT /evidence="ECO:0000259|Pfam:PF15985"
SQ SEQUENCE 296 AA; 33438 MW; 0374E6BD35EB0EA9 CRC64;
MDEYPVINVR LAMNRVDFNL TGNEGIQTRL YTPGEEISNQ LDFLRGHGTY VDEDNTLRAA
VGGVLEKVNK LISVRPLKAR YQGEIGDVIV GRITEVQQKR WKVDTNSKLD SVLLLSSVNL
PGGELRRRSA EDEQTMRRYL QEGDLVCAEV QSIFADSSLS LHTRVLKYGK LSQGIMLKVP
PMLIQRKKTH FHYLENSTSL ILGNNGYVWI GANAQNADRS EGGFTEDLSH IPQENREVCT
RLRNCILILA QCNMLLSDTS VTYAYEESMK YTVSELLESE AMVDISLLTH QRLAQQ
//
