ID E2BWN8_HARSA Unreviewed; 428 AA.
AC E2BWN8;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Serine palmitoyltransferase 2 {ECO:0000313|EMBL:EFN79893.1};
GN ORFNames=EAI_14945 {ECO:0000313|EMBL:EFN79893.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN79893.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN79893.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-II pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00008392}.
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DR EMBL; GL451165; EFN79893.1; -; Genomic_DNA.
DR AlphaFoldDB; E2BWN8; -.
DR STRING; 610380.E2BWN8; -.
DR EnsemblMetazoa; XM_011148173.3; XP_011146475.1; LOC105187399.
DR InParanoid; E2BWN8; -.
DR OMA; ADVEIMM; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR13693; CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE; 1.
DR PANTHER; PTHR13693:SF3; LD36009P; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Transferase {ECO:0000313|EMBL:EFN79893.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 117..420
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
SQ SEQUENCE 428 AA; 48220 MW; 1B806FB49C077525 CRC64;
MELEKEYGTA EPRSKESAEK VPFVTAVLTH LGFYILMFLG FINYLFFVPK VALEKNREGY
APLYDNFEKF YLRYVYRRVR DCWNKPICSV PGATVTLKDR VTHDYGWTFQ FTGTQTKCIN
LGSYNYLEFS KNTGKCAMDS INTLKKFGCA TYSTRLELGT MTIHQELEKL TAKFMGVEDA
IVFGMGFATN ALSLPSLVGK GCLVLSDAKN HVSLIHGMRL SGATVRVFKH NNVKDLEECL
KKAVVFGQPR TGEPWKKILI VVEGIYSMEG SIVCLPEIIE LKKKYKAYLY LDEAHSIGFM
GKHGRGICNY YDIDPRNVDI LTGSFAKSFG AIGGYIAGTK ALINHLRIYC HAHTYASAMS
PPVAQQIISA MQIIVGEGGM DEGKKRIKQL ARNTRYFRRR LNQIGVIIYG NEDSPIVPML
VYMYSKIG
//
