ID E2FTH0_9THEO Unreviewed; 450 AA.
AC E2FTH0;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN Name=recG {ECO:0000313|EMBL:ADN19260.1};
OS Thermoanaerobacter uzonensis.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=447593 {ECO:0000313|EMBL:ADN19260.1};
RN [1] {ECO:0000313|EMBL:ADN19260.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JW/IW_H608_3 {ECO:0000313|EMBL:ADN19260.1};
RA Wagner I.D., Varghese L., Wiegel J.;
RT "Universally conserved protein coding gene sequence heterogeneity among
RT Thermoanaerobacter uzonensis isolates from geothermal springs of Kamchatka,
RT Russian Far East.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504}.
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DR EMBL; HM190739; ADN19260.1; -; Genomic_DNA.
DR AlphaFoldDB; E2FTH0; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd17992; DEXHc_RecG; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR033454; RecG_wedge.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ADN19260.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 165..326
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 349..450
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADN19260.1"
FT NON_TER 450
FT /evidence="ECO:0000313|EMBL:ADN19260.1"
SQ SEQUENCE 450 AA; 51027 MW; DF8E0FB6C21B901D CRC64;
IGEEYIINGK LQFKYGQLIV ENPVLEKSED FRLNTGRIVP IYGLTEGLTQ NAIRKIMFNA
LHDYVQEIEE FFDEEFLFEK GLMDIKNALI NINFPQNEAY LEQAKYRFKY QELFLLQMAL
FLVKRSVKGK KGIKFERVEL KPFLVGLPFK LTSAQIKVLK EIIADMNSHK VMNRLVQGDV
GSGKTVVAAC SMYIAVKNGY QVAMMAPTEI LAKQHYYTLK ELFRNTDIKI GLLSGSISPS
NKKEVLEKIK NGDYDIVVGT HALIEDDVIF NNLGLCITDE QHRFGVRQRA LLTKKGENPD
VLVMTATPIP RTLALILYGD LDISIIDQLP PGRKKVKTYV ISSSVRKKAY EFAMKEVKKG
RQVYVVCPLI EESDKINAMS AEIVYREIYK DAFKEAKVGL LHGKMNDSDK EKVMEEFVNG
KIDILVSTTV IEVGVNVPNA TVMIVENAEM
//
