ID E2MTW1_CORAY Unreviewed; 1339 AA.
AC E2MTW1;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:EEB64065.1};
GN Name=hrpA {ECO:0000313|EMBL:EEB64065.1};
GN ORFNames=CORAM0001_0859 {ECO:0000313|EMBL:EEB64065.1};
OS Corynebacterium amycolatum SK46.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=553204 {ECO:0000313|EMBL:EEB64065.1, ECO:0000313|Proteomes:UP000003275};
RN [1] {ECO:0000313|EMBL:EEB64065.1, ECO:0000313|Proteomes:UP000003275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK46 {ECO:0000313|EMBL:EEB64065.1,
RC ECO:0000313|Proteomes:UP000003275};
RA Sebastian Y., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEB64065.1}.
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DR EMBL; ABZU01000001; EEB64065.1; -; Genomic_DNA.
DR eggNOG; COG1643; Bacteria.
DR Proteomes; UP000003275; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EEB64065.1};
KW Hydrolase {ECO:0000313|EMBL:EEB64065.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 112..275
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 311..481
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1339 AA; 150075 MW; 88EF61EFAC836D1E CRC64;
MTTPSRSDKP APRAQSGNRH SGHRNSARPQ HSGKPAKDTR KKELYQLADQ LPIREAQSFR
RRLKRASAPK ALSAISADLS FALERLEDRR KAIPRITYPA QLPVSARHDD IAEAIENNQV
VIIAGETGSG KTTQIPKICL ELGRGVRGKI GHTQPRRIAA RSVAERIAHE LGEKIGQHVG
YAVRFDDRVG KDTCIKLMTD GILLAEIGRD RLLREYDTII IDEAHERSLN IDFLLGYLKH
ILPQRPDLKI IITSATIDPE RFARHFSPDD EHPAPIIEVS GRTYPVEIRY RPLVRTVVAK
NGQEKEVAIE QIDGVIAACE ELMRLGDGDI LVFFSGEREI REAAEAIEGK HWKGVEAVPL
FGRLSNAEQH RIFTPHSGRR IVLATNIAET SLTVPGIEYV VDTGTARISR YSTRTKVQRL
PVEDISQASA NQRSGRCGRV ADGVAIRLYS EEDYLSRPEF TDPEILRTNL ASVVLQMISL
RLGAIEDFPF VQPPEHKAIR DGINLLTELQ AITTTSGSGA PELTDIGRQI ARIPVDPRLA
RMLVEGYENT TLGAVTVIVA ALSLQDVRER PLEFQAQADQ LHARFKDTTS DFNSLLKLWE
YLEEKRRELS GNQFRKMCKR EYLHYLRVRE WQDLVRQLHQ ATAELGWHLS ARSSTSGVDN
PDEVAKSLLP GLLSMIGTRE GEGKEFTGTR NTKFLIHPSS ALAKKPPRWV MAAEIVETSR
TFARNVGTIQ PQWVEKVAPH LLKHQYSEPH WSTKRGAAMA YQKSTLYGVP VVVDRLVPYH
RVDADAARSI FIRSALVDGE WNTHHEFFKN NQDKLAEAEK IEEKQRSRGI VVDDDVLYAF
YDSKLPASIT TAANFDRWWK KTKPKQPNLL DFDPNKLLNP EAGDIDDNAF PEMWQQGSVE
FSLSYKFEPG APDDGVTLRV PVPLLAGLRE DGFDWQVPGL RSELAEAYIR TLPKALRKSV
VPAPDFARRA LETMTPYSGR FVDVFADALR RLGGSGINGA DFAPSKLPAH LRFNYAVVDR
HGKIVDQSRN LAALRDKHAT TVSTAVSKRS KSAAREAVKK WTSDNLGAVS ETVKSTVDGQ
SVTMYPTLVT TKDGVAIEVK PTKAQAEATL ATTNLTMLLR DCPVNSAQMT KGLPLQQRVG
VDAWPHGGAD GLVEDCRVAV IRDRMMAAGG PVRDPKEFDK LLEHVRSGVA SEVRQLVVGV
AQAMPRYVSV VNQLNKWEGD AIDDMRRQLE FMFPKGAVAR HGWQHLRHLP RYLQAMEIRL
EEMNRDPDRD AEREDEVAEA REYLAAKLQQ LPKARSNSAE VRDIQWLIQE LRVSLFAQRL
GTAQSVSLTR VKKRVDKLR
//
