ID E2QLF0_ECOLX Unreviewed; 410 AA.
AC E2QLF0; A0A236UBF0;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:ANO92377.1, ECO:0000313|EMBL:MBA6242587.1};
DE EC=2.7.1.22 {ECO:0000313|EMBL:MBA6242587.1};
DE EC=2.7.7.1 {ECO:0000313|EMBL:ANO92377.1, ECO:0000313|EMBL:AZZ29566.1};
DE SubName: Full=Trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR {ECO:0000313|EMBL:AZZ29566.1};
GN Name=nadR {ECO:0000313|EMBL:MBA6242587.1};
GN Synonyms=nadR_1 {ECO:0000313|EMBL:STE03251.1};
GN ORFNames=AAG81_001581 {ECO:0000313|EMBL:EFL5809205.1}, B6R15_002704
GN {ECO:0000313|EMBL:EFM7861438.1}, B6R31_004048
GN {ECO:0000313|EMBL:EGD0650324.1}, BCB93_001675
GN {ECO:0000313|EMBL:EFI6952063.1}, BK383_08095
GN {ECO:0000313|EMBL:OJR55601.1}, BO178_003798
GN {ECO:0000313|EMBL:EFG2489245.1}, CIG67_11015
GN {ECO:0000313|EMBL:RVE13491.1}, CV83915_01581
GN {ECO:0000313|EMBL:ATZ31928.1}, CY655_27950
GN {ECO:0000313|EMBL:AZZ29566.1}, CYM75_004229
GN {ECO:0000313|EMBL:EFB5924084.1}, D3G36_11275
GN {ECO:0000313|EMBL:EFA4418442.1}, D9D43_18820
GN {ECO:0000313|EMBL:MGE15597.1}, DD762_00090
GN {ECO:0000313|EMBL:PWH64570.1}, DIV22_03135
GN {ECO:0000313|EMBL:PZZ73601.1}, DU321_02705
GN {ECO:0000313|EMBL:RRL50799.1}, E4K51_15665
GN {ECO:0000313|EMBL:MQS31584.1}, EAN77_19725
GN {ECO:0000313|EMBL:EAB1385572.1}, F7F11_02995
GN {ECO:0000313|EMBL:KAB0126758.1}, F7N46_11300
GN {ECO:0000313|EMBL:EFE8673713.1}, F9413_04155
GN {ECO:0000313|EMBL:EFH4959735.1}, F9B07_04465
GN {ECO:0000313|EMBL:MTE88098.1}, FKO60_13580
GN {ECO:0000313|EMBL:TZE48254.1}, FOI11_013755
GN {ECO:0000313|EMBL:QOY29512.1}, FOI11_21925
GN {ECO:0000313|EMBL:MBA6242587.1}, FPI65_27125
GN {ECO:0000313|EMBL:NDR94874.1}, FTV92_14265
GN {ECO:0000313|EMBL:QED70949.1}, FZU14_06680
GN {ECO:0000313|EMBL:EFD6883908.1}, G3V95_16315
GN {ECO:0000313|EMBL:NEM87046.1}, G5603_21460
GN {ECO:0000313|EMBL:NGE90722.1}, GGB84_004002
GN {ECO:0000313|EMBL:HAG5772254.1}, GJ11_27515
GN {ECO:0000313|EMBL:ANO92377.1}, GKF66_03450
GN {ECO:0000313|EMBL:MSI67883.1}, GOP25_18405
GN {ECO:0000313|EMBL:EFH5894187.1}, GQM13_11690
GN {ECO:0000313|EMBL:MWL04096.1}, HEP34_004790
GN {ECO:0000313|EMBL:EFM1448345.1}, HI055_000958
GN {ECO:0000313|EMBL:HAI2140651.1}, HL563_03685
GN {ECO:0000313|EMBL:HAJ0832851.1}, HL601_06775
GN {ECO:0000313|EMBL:HAJ0995310.1}, HVW04_11180
GN {ECO:0000313|EMBL:QMP45402.1}, HX086_13615
GN {ECO:0000313|EMBL:MDM1661585.1}, KV259_000755
GN {ECO:0000313|EMBL:EHS3284677.1}, KV317_004645
GN {ECO:0000313|EMBL:EHS3598547.1}, KV371_004663
GN {ECO:0000313|EMBL:EHS3810794.1}, KV406_004653
GN {ECO:0000313|EMBL:EHS3999718.1}, KV449_001410
GN {ECO:0000313|EMBL:EHS4167361.1}, KV455_004559
GN {ECO:0000313|EMBL:EHS4136060.1}, KV463_001116
GN {ECO:0000313|EMBL:EHS4172244.1}, KV469_003293
GN {ECO:0000313|EMBL:EHS4179549.1}, KV499_004673
GN {ECO:0000313|EMBL:EHS4296139.1}, KV500_004623
GN {ECO:0000313|EMBL:EHS4316076.1}, NCTC10082_01585
GN {ECO:0000313|EMBL:STE03251.1}, NCTC10089_04277
GN {ECO:0000313|EMBL:VTR23963.1}, NCTC7927_04709
GN {ECO:0000313|EMBL:STF95767.1}, NCTC8621_04390
GN {ECO:0000313|EMBL:STH84313.1}, NCTC9044_02949
GN {ECO:0000313|EMBL:VED11560.1}, NCTC9706_01606
GN {ECO:0000313|EMBL:STN84589.1}, O5851_09205
GN {ECO:0000313|EMBL:MCZ5093822.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:MBA6242587.1, ECO:0000313|Proteomes:UP000581425};
RN [1] {ECO:0000313|EMBL:ANO92377.1, ECO:0000313|Proteomes:UP000092566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=06-00048 {ECO:0000313|EMBL:ANO92377.1,
RC ECO:0000313|Proteomes:UP000092566};
RA Timme R., Allard M.W., Strain E., Evans P.S., Lorenz S., Brown E.;
RT "Whole genome shotgun sequencing of cultured foodborne pathogen.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OJR55601.1, ECO:0000313|Proteomes:UP000184277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=570 {ECO:0000313|EMBL:OJR55601.1,
RC ECO:0000313|Proteomes:UP000184277};
RA Wang Y., Zhang R., Li J., Wu Z., Wenjuan Y., Schwarz S., Tyrrell J.,
RA Zheng Y., Wang S., Shen Z., Liu Z., Lei L., Li M., Zhang Q., Wu C.,
RA Zhang Q., Wu Y., Walsh T., Shen J.;
RT "Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1
RT in Chinese poultry production.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RVE13491.1, ECO:0000313|Proteomes:UP000288459}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCPM 6219 {ECO:0000313|EMBL:RVE13491.1,
RC ECO:0000313|Proteomes:UP000288459};
RA Liu S.-L., Zhou Y.-J., Zhao M.-F.;
RT "Sequencing of Escherichia coli CCPM 6219.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:ATZ31928.1, ECO:0000313|Proteomes:UP000236551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CV839-15 {ECO:0000313|EMBL:ATZ31928.1,
RC ECO:0000313|Proteomes:UP000236551};
RA Li Z., Song N., Li W., Philip H.R., Bu Z., Siguo L.;
RT "Escherichia coli CV839-15 Genome sequencing and assembly.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AZZ29566.1, ECO:0000313|Proteomes:UP000284592}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E-1246 {ECO:0000313|EMBL:AZZ29566.1,
RC ECO:0000313|Proteomes:UP000284592};
RA Bikkarolla S.K., Nordberg V., Kabir M.H., Muller V., Fritzsche J.,
RA Ambjornsson T., Giske C.G., Naver L., Sandegren L., Westerlund F.;
RT "Combining optical DNA mapping and long-read sequencing for full genomic
RT characterization of plasmids in a nosocomial resistance outbreak.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:HAG5772254.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1839 {ECO:0000313|EMBL:HAG5772254.1}, BCW_4213
RC {ECO:0000313|EMBL:HAI2140651.1}, EC00605
RC {ECO:0000313|EMBL:HAJ0995310.1}, and EC00618
RC {ECO:0000313|EMBL:HAJ0832851.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [7] {ECO:0000313|EMBL:PWH64570.1, ECO:0000313|Proteomes:UP000245761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8S56 {ECO:0000313|EMBL:PWH64570.1,
RC ECO:0000313|Proteomes:UP000245761};
RA Xu A., Tilman S., Wisser-Parker K., Scullen O.J., Sommers C.;
RT "Draft Genomic Sequencing Of Potential Extraintestinal Pathogenic
RT Escherichia coli B8S56 Isolated from Retail Chicken Skin.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:PZZ73601.1, ECO:0000313|Proteomes:UP000248865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=14-391 {ECO:0000313|EMBL:PZZ73601.1,
RC ECO:0000313|Proteomes:UP000248865};
RA Karnisova L., Nunvar J., Marejkova M., Mellmann A., Drevinek P.,
RA Blahova K., Bielaszewska M.;
RT "Genomic sequencing of EHEC O26 New European Clone.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|Proteomes:UP000254043, ECO:0000313|Proteomes:UP000254460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10082 {ECO:0000313|EMBL:STE03251.1,
RC ECO:0000313|Proteomes:UP000255164}, NCTC7927
RC {ECO:0000313|EMBL:STF95767.1, ECO:0000313|Proteomes:UP000254043},
RC NCTC8621 {ECO:0000313|EMBL:STH84313.1,
RC ECO:0000313|Proteomes:UP000255093}, and NCTC9706
RC {ECO:0000313|EMBL:STN84589.1, ECO:0000313|Proteomes:UP000254460};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:EFG2489245.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=278157 {ECO:0000313|EMBL:EFG2489245.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|EMBL:EFM7861438.1, ECO:0000313|Proteomes:UP000587626}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CFSAN046653 {ECO:0000313|EMBL:EFI6952063.1}, Elk_RLE1_A7
RC {ECO:0000313|EMBL:EHS3284677.1}, Elk_RLE1_D5
RC {ECO:0000313|EMBL:EHS4167361.1}, Elk_RLE1_D7
RC {ECO:0000313|EMBL:EHS3598547.1}, Elk_RLE1_D8
RC {ECO:0000313|EMBL:EHS4296139.1}, Elk_RLE1_E7
RC {ECO:0000313|EMBL:EHS4172244.1}, Elk_RLE1_F6
RC {ECO:0000313|EMBL:EHS3999718.1}, Elk_RLE1_G8
RC {ECO:0000313|EMBL:EHS4136060.1}, Elk_RLE1_H7
RC {ECO:0000313|EMBL:EHS4179549.1}, Elk_RLE2_A10
RC {ECO:0000313|EMBL:EHS3810794.1}, Elk_RLE2_C11
RC {ECO:0000313|EMBL:EHS4316076.1}, NC_STEC178
RC {ECO:0000313|EMBL:EGD0650324.1}, NC_STEC194
RC {ECO:0000313|EMBL:EFM7861438.1, ECO:0000313|Proteomes:UP000587626},
RC PSU-1190 {ECO:0000313|EMBL:EFA4418442.1,
RC ECO:0000313|Proteomes:UP000591371}, PSU-2243
RC {ECO:0000313|EMBL:EFH5894187.1, ECO:0000313|Proteomes:UP000531813},
RC and PSU-2464 {ECO:0000313|EMBL:EFM1448345.1,
RC ECO:0000313|Proteomes:UP000519182};
RG GenomeTrakr network: Whole genome sequencing for foodborne pathogen traceback;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [12] {ECO:0000313|EMBL:RRL50799.1, ECO:0000313|Proteomes:UP000272662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMB1727 {ECO:0000313|EMBL:RRL50799.1,
RC ECO:0000313|Proteomes:UP000272662};
RA Garretto A., Miller-Ensminger T., Wolfe A.J., Putonti C.;
RT "E. coli isolates of the female bladder.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [13] {ECO:0000313|EMBL:MQS31584.1, ECO:0000313|Proteomes:UP000460351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RXD010 {ECO:0000313|EMBL:MQS31584.1,
RC ECO:0000313|Proteomes:UP000460351};
RX PubMed=31652858;
RA Peng Z., Li X., Hu Z., Li Z., Lv Y., Lei M., Wu B., Chen H., Wang X.;
RT "Characteristics of Carbapenem-Resistant and Colistin-Resistant Escherichia
RT coli Co-Producing NDM-1 and MCR-1 from Pig Farms in China.";
RL Microorganisms 7:0-E482(2019).
RN [14] {ECO:0000313|EMBL:MSI67883.1, ECO:0000313|Proteomes:UP000438958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A382 {ECO:0000313|EMBL:MSI67883.1,
RC ECO:0000313|Proteomes:UP000438958};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
RN [15] {ECO:0000313|EMBL:KAB0126758.1, ECO:0000313|Proteomes:UP000327073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=STEC_170836 {ECO:0000313|EMBL:KAB0126758.1,
RC ECO:0000313|Proteomes:UP000327073};
RA Abdalhamid B., Mccutchen E.L., Bouska A.C., Hinrichs S.H., Iwen P.C.;
RT "Whole Genome Sequencing of Shiga-Toxin Escherichia coli Strains from
RT Nebraska.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN [16] {ECO:0000313|EMBL:VTR23963.1, ECO:0000313|Proteomes:UP000406392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10089 {ECO:0000313|EMBL:VTR23963.1,
RC ECO:0000313|Proteomes:UP000406392}, and NCTC9044
RC {ECO:0000313|EMBL:VED11560.1, ECO:0000313|Proteomes:UP000271797};
RG Pathogen Informatics;
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
RN [17] {ECO:0000313|EMBL:TZE48254.1, ECO:0000313|Proteomes:UP000324120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=347 {ECO:0000313|EMBL:TZE48254.1,
RC ECO:0000313|Proteomes:UP000324120};
RA Cormier A.C., Chalmer G., Cook S.R., Zaheer R., Hannon S.J., Booker C.W.,
RA Read R., Gow S.P., Mcallister T.A., Boerlin P.;
RT "The presence and diversity of blaCTX-M among Escherichia coli from urban
RT wastewater and feedlot cattle, in Alberta, Canada.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [18] {ECO:0000313|EMBL:QED70949.1, ECO:0000313|Proteomes:UP000321760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCYU-25-82 {ECO:0000313|EMBL:QED70949.1,
RC ECO:0000313|Proteomes:UP000321760};
RA Hsu C.-Y., Huang W.-C., Lauderdale T.-L.;
RT "Plasmid- and chromosome-located mcr-3 in mcr-1-positive Escherichia coli
RT from diseased swine, Taiwan.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [19] {ECO:0000313|EMBL:QED70949.1, ECO:0000313|Proteomes:UP000321760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCYU-25-82 {ECO:0000313|EMBL:QED70949.1,
RC ECO:0000313|Proteomes:UP000321760};
RA Chen F.-J., Wu H.-C., Liao Y.-C., Kuo S.-C.;
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [20] {ECO:0000313|EMBL:HAJ0832851.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=1839 {ECO:0000313|EMBL:HAG5772254.1}, BCW_4213
RC {ECO:0000313|EMBL:HAI2140651.1}, EC00605
RC {ECO:0000313|EMBL:HAJ0995310.1}, and EC00618
RC {ECO:0000313|EMBL:HAJ0832851.1};
RG NCBI Pathogen Detection Project;
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [21] {ECO:0000313|EMBL:MTE88098.1, ECO:0000313|Proteomes:UP000486847}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SE161 {ECO:0000313|EMBL:MTE88098.1,
RC ECO:0000313|Proteomes:UP000486847};
RA Ghatak S., Milton A.P., Rhetso K., Purkait D., Das S., Puro K.-U.,
RA Shakuntala I., Sen A., Sanjukta R., Priya G.B., Mawlong M., Lyngdoh V.,
RA Rynghang J., Mawphlang B.L.;
RT "Comparative genomic analysis of antimicrobial resistant Escherichia coli
RT of diverse origin.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
RN [22] {ECO:0000313|EMBL:MWL04096.1, ECO:0000313|Proteomes:UP000430081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10432wG7 {ECO:0000313|EMBL:MWL04096.1,
RC ECO:0000313|Proteomes:UP000430081};
RA Subbiah M., Call D.;
RT "Enteriobacteria Tanzani isolates_10432.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
RN [23] {ECO:0000313|EMBL:EFH4959735.1, ECO:0000313|Proteomes:UP000543424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=19MD07CB01-EC {ECO:0000313|EMBL:EFD6883908.1,
RC ECO:0000313|Proteomes:UP000531962}, CVM N17EC0060
RC {ECO:0000313|EMBL:MGE15597.1, ECO:0000313|Proteomes:UP000272336}, CVM
RC N19EC0130 {ECO:0000313|EMBL:EFH4959735.1,
RC ECO:0000313|Proteomes:UP000543424}, and FSIS11923834
RC {ECO:0000313|EMBL:EFE8673713.1, ECO:0000313|Proteomes:UP000533482};
RG NARMS: The National Antimicrobial Resistance Monitoring System;
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
RN [24] {ECO:0000313|EMBL:NDR94874.1, ECO:0000313|Proteomes:UP000471490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11230 {ECO:0000313|EMBL:NDR94874.1,
RC ECO:0000313|Proteomes:UP000471490};
RX PubMed=32021174;
RA Kedziora A., Wernecki M., Korzekwa K., Speruda M., Gerasymchuk Y.,
RA Lukowiak A., Bugla-Ploskonska G.;
RT "Consequences Of Long-Term Bacteria's Exposure To Silver Nanoformulations
RT With Different PhysicoChemical Properties.";
RL Int J Nanomedicine 15:199-213(2020).
RN [25] {ECO:0000313|EMBL:NGE90722.1, ECO:0000313|Proteomes:UP000472856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ECM_75 {ECO:0000313|EMBL:NGE90722.1,
RC ECO:0000313|Proteomes:UP000472856};
RA Tokajian S., El Chaar M., El Khoury M.;
RT "WGS of Carbapenem-Resistant Enterobacteriaceae.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
RN [26] {ECO:0000313|EMBL:NEM87046.1, ECO:0000313|Proteomes:UP000469708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8375wC2 {ECO:0000313|EMBL:NEM87046.1,
RC ECO:0000313|Proteomes:UP000469708};
RA Subbiah M., Call D.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
RN [27] {ECO:0000313|EMBL:EFB5924084.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=04-3227 {ECO:0000313|EMBL:EFL5809205.1}, 2009C-3117
RC {ECO:0000313|EMBL:EFB5924084.1}, and PNUSAE017941
RC {ECO:0000313|EMBL:EAB1385572.1};
RG PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
RN [28] {ECO:0000313|EMBL:QMP45402.1, ECO:0000313|Proteomes:UP000514715}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHB07-C04 {ECO:0000313|EMBL:QMP45402.1,
RC ECO:0000313|Proteomes:UP000514715};
RA Shaw L.P.;
RT "REHAB project genomes.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
RN [29] {ECO:0000313|EMBL:MDM1661585.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=70 {ECO:0000313|EMBL:MDM1661585.1};
RA Dong N.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
RN [30] {ECO:0000313|EMBL:MBA6242587.1, ECO:0000313|Proteomes:UP000581425}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1409 {ECO:0000313|EMBL:MBA6242587.1,
RC ECO:0000313|Proteomes:UP000581425};
RA Ekesi N.S., Alrubaye A., Rhoads D.;
RT "Analysis of Genomes of Bacterial Isolates from Lameness Outbreaks in
RT Broilers.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
RN [31] {ECO:0000313|EMBL:QOY29512.1, ECO:0000313|Proteomes:UP000581425}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1409 {ECO:0000313|EMBL:QOY29512.1,
RC ECO:0000313|Proteomes:UP000581425};
RA Rhoads D., Ekesi N.S.;
RT "Analysis of Genomes of Bacterial Isolates from Lameness Outbreaks in
RT Broilers.";
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
RN [32] {ECO:0000313|EMBL:MDM1661585.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=70 {ECO:0000313|EMBL:MDM1661585.1};
RX PubMed=34801490;
RA Dong N., Zeng Y., Cai C., Sun C., Lu J., Liu C., Zhou H., Sun Q., Shu L.,
RA Wang H., Wang Y., Wang S., Wu C., Chan E.W., Chen G., Shen Z., Chen S.,
RA Zhang R.;
RT "Prevalence, transmission, and molecular epidemiology of tet(X)-positive
RT bacteria among humans, animals, and environmental niches in China: An
RT epidemiological, and genomic-based study.";
RL Sci. Total Environ. 818:0-0(2022).
RN [33] {ECO:0000313|EMBL:MCZ5093822.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EC_E2BE_2_E_CuN_CeN {ECO:0000313|EMBL:MCZ5093822.1};
RA Sanderson H., Nnajibe C., Mccarthy M., Rubin J., Dillon J., White A.P.;
RT "Genome Hybrid Assemblies of 274 Avian and Broiler Barn Environment
RT Associated Escherichia coli Isolated from Saskatchewan Broiler Farms.";
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP015229; ANO92377.1; -; Genomic_DNA.
DR EMBL; CP024978; ATZ31928.1; -; Genomic_DNA.
DR EMBL; CP025573; AZZ29566.1; -; Genomic_DNA.
DR EMBL; AAADQZ010000032; EAB1385572.1; -; Genomic_DNA.
DR EMBL; AASATZ010000012; EFA4418442.1; -; Genomic_DNA.
DR EMBL; AASGFF010000024; EFB5924084.1; -; Genomic_DNA.
DR EMBL; AASKVF010000006; EFD6883908.1; -; Genomic_DNA.
DR EMBL; AASOHJ010000012; EFE8673713.1; -; Genomic_DNA.
DR EMBL; AASSIV010000027; EFG2489245.1; -; Genomic_DNA.
DR EMBL; AASWBF010000004; EFH4959735.1; -; Genomic_DNA.
DR EMBL; AASWIS010000022; EFH5894187.1; -; Genomic_DNA.
DR EMBL; AASZRA010000006; EFI6952063.1; -; Genomic_DNA.
DR EMBL; AATIFT010000004; EFL5809205.1; -; Genomic_DNA.
DR EMBL; AATJYL010000070; EFM1448345.1; -; Genomic_DNA.
DR EMBL; AATLXB010000029; EFM7861438.1; -; Genomic_DNA.
DR EMBL; AAVQAW010000021; EGD0650324.1; -; Genomic_DNA.
DR EMBL; ABBDFQ010000003; EHS3284677.1; -; Genomic_DNA.
DR EMBL; ABBDHW010000040; EHS3598547.1; -; Genomic_DNA.
DR EMBL; ABBDJP010000041; EHS3810794.1; -; Genomic_DNA.
DR EMBL; ABBDLD010000040; EHS3999718.1; -; Genomic_DNA.
DR EMBL; ABBDMN010000037; EHS4136060.1; -; Genomic_DNA.
DR EMBL; ABBDMM010000005; EHS4167361.1; -; Genomic_DNA.
DR EMBL; ABBDMP010000004; EHS4172244.1; -; Genomic_DNA.
DR EMBL; ABBDMO010000018; EHS4179549.1; -; Genomic_DNA.
DR EMBL; ABBDNM010000041; EHS4296139.1; -; Genomic_DNA.
DR EMBL; ABBDNR010000039; EHS4316076.1; -; Genomic_DNA.
DR EMBL; DAAYTU010000030; HAG5772254.1; -; Genomic_DNA.
DR EMBL; DABDSA010000003; HAI2140651.1; -; Genomic_DNA.
DR EMBL; DABGYN010000002; HAJ0832851.1; -; Genomic_DNA.
DR EMBL; DABGZR010000005; HAJ0995310.1; -; Genomic_DNA.
DR EMBL; VZEL01000002; KAB0126758.1; -; Genomic_DNA.
DR EMBL; JACGTG010000002; MBA6242587.1; -; Genomic_DNA.
DR EMBL; JAPXEC010000002; MCZ5093822.1; -; Genomic_DNA.
DR EMBL; JACAMR010000027; MDM1661585.1; -; Genomic_DNA.
DR EMBL; RNLZ01000040; MGE15597.1; -; Genomic_DNA.
DR EMBL; SQQU01000020; MQS31584.1; -; Genomic_DNA.
DR EMBL; WKUE01000003; MSI67883.1; -; Genomic_DNA.
DR EMBL; WCEW01000003; MTE88098.1; -; Genomic_DNA.
DR EMBL; WTMQ01000003; MWL04096.1; -; Genomic_DNA.
DR EMBL; VLTB01000448; NDR94874.1; -; Genomic_DNA.
DR EMBL; JAAGYI010000026; NEM87046.1; -; Genomic_DNA.
DR EMBL; JAAJRI010000023; NGE90722.1; -; Genomic_DNA.
DR EMBL; MOKI01000016; OJR55601.1; -; Genomic_DNA.
DR EMBL; QEMT01000001; PWH64570.1; -; Genomic_DNA.
DR EMBL; QFSS01000011; PZZ73601.1; -; Genomic_DNA.
DR EMBL; CP042627; QED70949.1; -; Genomic_DNA.
DR EMBL; CP057975; QMP45402.1; -; Genomic_DNA.
DR EMBL; CP063369; QOY29512.1; -; Genomic_DNA.
DR EMBL; RRVG01000002; RRL50799.1; -; Genomic_DNA.
DR EMBL; NPIM01000124; RVE13491.1; -; Genomic_DNA.
DR EMBL; UFZA01000001; STE03251.1; -; Genomic_DNA.
DR EMBL; UGAK01000003; STF95767.1; -; Genomic_DNA.
DR EMBL; UGBW01000003; STH84313.1; -; Genomic_DNA.
DR EMBL; UGGJ01000004; STN84589.1; -; Genomic_DNA.
DR EMBL; VHKY01000008; TZE48254.1; -; Genomic_DNA.
DR EMBL; LR134238; VED11560.1; -; Genomic_DNA.
DR EMBL; CABEEY010000003; VTR23963.1; -; Genomic_DNA.
DR RefSeq; WP_000093813.1; NZ_WXYY01000001.1.
DR PATRIC; fig|562.10824.peg.1381; -.
DR OMA; QDPFRYW; -.
DR Proteomes; UP000092566; Chromosome.
DR Proteomes; UP000184277; Unassembled WGS sequence.
DR Proteomes; UP000236551; Chromosome.
DR Proteomes; UP000245761; Unassembled WGS sequence.
DR Proteomes; UP000248865; Unassembled WGS sequence.
DR Proteomes; UP000254043; Unassembled WGS sequence.
DR Proteomes; UP000254460; Unassembled WGS sequence.
DR Proteomes; UP000255093; Unassembled WGS sequence.
DR Proteomes; UP000255164; Unassembled WGS sequence.
DR Proteomes; UP000271797; Chromosome 1.
DR Proteomes; UP000272336; Unassembled WGS sequence.
DR Proteomes; UP000272662; Unassembled WGS sequence.
DR Proteomes; UP000284592; Chromosome.
DR Proteomes; UP000288459; Unassembled WGS sequence.
DR Proteomes; UP000321760; Chromosome.
DR Proteomes; UP000324120; Unassembled WGS sequence.
DR Proteomes; UP000327073; Unassembled WGS sequence.
DR Proteomes; UP000406392; Unassembled WGS sequence.
DR Proteomes; UP000430081; Unassembled WGS sequence.
DR Proteomes; UP000438958; Unassembled WGS sequence.
DR Proteomes; UP000460351; Unassembled WGS sequence.
DR Proteomes; UP000469708; Unassembled WGS sequence.
DR Proteomes; UP000471490; Unassembled WGS sequence.
DR Proteomes; UP000472856; Unassembled WGS sequence.
DR Proteomes; UP000486847; Unassembled WGS sequence.
DR Proteomes; UP000514715; Chromosome.
DR Proteomes; UP000519182; Unassembled WGS sequence.
DR Proteomes; UP000531813; Unassembled WGS sequence.
DR Proteomes; UP000531962; Unassembled WGS sequence.
DR Proteomes; UP000533482; Unassembled WGS sequence.
DR Proteomes; UP000543424; Unassembled WGS sequence.
DR Proteomes; UP000581425; Unassembled WGS sequence.
DR Proteomes; UP000587626; Unassembled WGS sequence.
DR Proteomes; UP000591371; Unassembled WGS sequence.
DR Proteomes; UP000630371; Unassembled WGS sequence.
DR Proteomes; UP000702781; Unassembled WGS sequence.
DR Proteomes; UP000729274; Unassembled WGS sequence.
DR Proteomes; UP000730526; Unassembled WGS sequence.
DR Proteomes; UP000739847; Unassembled WGS sequence.
DR Proteomes; UP000753065; Unassembled WGS sequence.
DR Proteomes; UP000754717; Unassembled WGS sequence.
DR Proteomes; UP000759070; Unassembled WGS sequence.
DR Proteomes; UP000775646; Unassembled WGS sequence.
DR Proteomes; UP000779652; Unassembled WGS sequence.
DR Proteomes; UP000784110; Unassembled WGS sequence.
DR Proteomes; UP000813224; Unassembled WGS sequence.
DR Proteomes; UP000852798; Unassembled WGS sequence.
DR Proteomes; UP001082551; Unassembled WGS sequence.
DR Proteomes; UP001173742; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0050262; F:ribosylnicotinamide kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR CDD; cd02019; NK; 1.
DR CDD; cd02167; NMNAT_NadR; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR016429; NAD_NadR.
DR InterPro; IPR038727; NadR/Ttd14_AAA_dom.
DR InterPro; IPR006417; NadR_NMN_Atrans.
DR InterPro; IPR041749; NMNAT_NadR.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR NCBIfam; TIGR01526; nadR_NMN_Atrans; 1.
DR PANTHER; PTHR37512:SF1; AAA_28 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37512; TRIFUNCTIONAL NAD BIOSYNTHESIS/REGULATOR PROTEIN NADR; 1.
DR Pfam; PF13521; AAA_28; 1.
DR Pfam; PF01381; HTH_3; 1.
DR PIRSF; PIRSF004776; NadR_NMNAT/RNK; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:MBA6242587.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR004776-1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:MBA6242587.1};
KW Transferase {ECO:0000313|EMBL:MBA6242587.1}.
FT DOMAIN 7..62
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT BINDING 70..73
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
FT BINDING 77
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
FT BINDING 104
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
FT BINDING 144..157
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
FT BINDING 177..179
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
FT BINDING 204..206
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
FT BINDING 259..261
FT /ligand="NAD(+)"
FT /ligand_id="ChEBI:CHEBI:57540"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR004776-1"
SQ SEQUENCE 410 AA; 47332 MW; BCBC26CD3ABBF4E9 CRC64;
MSSFDYLKTA IKQQGCTLQQ VADASGMTKG YLSQLLNAKI KSPSAQKLEA LHRFLGLEFP
RQKKTIGVVF GKFYPLHTGH IYLIQRACSQ VDELHIIMGF DDTRDRALFE DSAMSQQPTV
PDRLRWLLQT FKYQKNIRIH AFNEEGMEPY PHGWDVWSNG IKKFMAEKGI QPDLIYTSEE
ADAPQYMEHL GIETVLVDPK RTFMSISGAQ IRENPFRYWE YIPTEVKPFF VRTVAILGGE
SSGKSTLVNK LANIFNTTSA WEYGRDYVFS HLGGDEIALQ YSDYDKIALG HAQYIDFAVK
YANKVAFIDT DFVTTQAFCK KYEGREHPFV QALIDEYRFD LVILLENNTP WVADGLRSLG
SSVDRKEFQN LLVEMLEENN IEFVRVEEDD YDSRFLRCVE LVREMMGEQR
//
