GenomeNet

Database: UniProt
Entry: E2RNZ5_CANLF
LinkDB: E2RNZ5_CANLF
Original site: E2RNZ5_CANLF 
ID   E2RNZ5_CANLF            Unreviewed;       536 AA.
AC   E2RNZ5;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 2.
DT   30-AUG-2017, entry version 58.
DE   SubName: Full=Cation channel sperm associated 2 {ECO:0000313|Ensembl:ENSCAFP00000019448};
GN   Name=CATSPER2 {ECO:0000313|Ensembl:ENSCAFP00000019448};
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
OC   Canis.
OX   NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00000019448, ECO:0000313|Proteomes:UP000002254};
RN   [1] {ECO:0000313|Ensembl:ENSCAFP00000019448, ECO:0000313|Proteomes:UP000002254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000019448,
RC   ECO:0000313|Proteomes:UP000002254};
RX   PubMed=16341006; DOI=10.1038/nature04338;
RG   Broad Sequencing Platform;
RA   Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
RA   Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C.,
RA   Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A.,
RA   Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E.F.,
RA   Alvarez P., Biagi T., Brockman W., Butler J., Chin C.-W., Cook A.,
RA   Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M.,
RA   Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L.,
RA   Koepfli K.-P., Parker H.G., Pollinger J.P., Searle S.M.J.,
RA   Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
RA   Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
RA   Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L.,
RA   Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A.,
RA   Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L.,
RA   Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N.,
RA   Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A.,
RA   Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N.,
RA   Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N.,
RA   Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K.,
RA   Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G.,
RA   Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E.,
RA   Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C.,
RA   Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L.,
RA   Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C.,
RA   Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T.,
RA   Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., LeVine S., Liu J.,
RA   Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J.,
RA   Marabella R., Maru K., Matthews C., McDonough S., Mehta T.,
RA   Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K.,
RA   Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J.,
RA   Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
RA   Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K.,
RA   Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F.,
RA   Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C.,
RA   Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S.,
RA   Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J.,
RA   Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S.,
RA   Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S.,
RA   Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T.,
RA   Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X.,
RA   Young G., Yu Q., Zainoun J., Zembek L., Zimmer A., Lander E.S.;
RT   "Genome sequence, comparative analysis and haplotype structure of the
RT   domestic dog.";
RL   Nature 438:803-819(2005).
RN   [2] {ECO:0000313|Ensembl:ENSCAFP00000019448}
RP   IDENTIFICATION.
RC   STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000019448};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCAFP00000019448}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAEX03016092; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9615.ENSCAFP00000019448; -.
DR   PaxDb; E2RNZ5; -.
DR   Ensembl; ENSCAFT00000020945; ENSCAFP00000019448; ENSCAFG00000013189.
DR   eggNOG; ENOG410INF6; Eukaryota.
DR   eggNOG; ENOG4111GC6; LUCA.
DR   GeneTree; ENSGT00760000119325; -.
DR   InParanoid; E2RNZ5; -.
DR   OMA; TLEVAAW; -.
DR   OrthoDB; EOG091G0I4O; -.
DR   TreeFam; TF343585; -.
DR   Reactome; R-CFA-1300642; Sperm Motility And Taxes.
DR   Proteomes; UP000002254; Chromosome 30.
DR   Bgee; ENSCAFG00000013189; -.
DR   GO; GO:0036128; C:CatSper complex; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:GO_Central.
DR   GO; GO:0030317; P:flagellated sperm motility; IEA:InterPro.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   GO; GO:0019228; P:neuronal action potential; IBA:GO_Central.
DR   InterPro; IPR028747; CatSper2.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   PANTHER; PTHR10037:SF271; PTHR10037:SF271; 1.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002254};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002254};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    133       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    153    176       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    183    202       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    247    267       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    287    307       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    319    345       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      112    353       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   536 AA;  62668 MW;  33070ECDA5A4BA7C CRC64;
     MATSHPTGHV QLPRADAIRS RLIDTFSLIE HLQGLSQAVP RHTIREIVDP SGQKKLMLGD
     QHQLVRFSIK PRHVERITRA RRLMSRLRVR YSQRPPLSLW AGWVLECKKT GPLFTNFIIF
     LIFLNTIVLM VEIELLESSN TKLWSLKLTL EVAAWFILLI FILEILLMWI SSFFLFWKNA
     WNVFDFVVTV SSLLPEVVVL VGVTGQSVWL QLLRICRVLR SLKLFARFRQ IRVIILALMR
     ALKSMTFLLM LLLIFFYIFA VTGVYFFEDY TRSTRQDLEY HMFFSDLLNS LVTVFILFTM
     DHWYALLQDT WKVPEVSRAF SSIYVILWLL LGSIIFRNII VAMMVTNFQN IRNELNEEMT
     HLEVQHKADI FKRQIIQRRQ NLSPEAMRSS LSKVDARNAN QQRESVDLSK AFEEESKHNA
     DEEGSRAPVS KTKASLSKMK KSSSSPSSHS SYFSSSSYSS SSDSRYVDPI GQLDWETHVH
     QNLPGLMQMD QDDQVVWPRD SLFRYFELLE KLQYNLEERK QLQEFAVQAL MNFEDK
//
DBGET integrated database retrieval system