ID E2RTQ4_GIAIC Unreviewed; 293 AA.
AC E2RTQ4;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Qa-SNARE 1 {ECO:0000313|EMBL:KAE8303537.1};
DE SubName: Full=Syntaxin-like protein 1 {ECO:0000313|EMBL:EDO80681.1};
GN ORFNames=GL50803_007309 {ECO:0000313|EMBL:KAE8303537.1}, GL50803_7309
GN {ECO:0000313|EMBL:EDO80681.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO80681.1};
RN [1] {ECO:0000313|EMBL:EDO80681.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO80681.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8303537.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8303537.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO80681.1}.
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DR EMBL; AACB02000008; EDO80681.1; -; Genomic_DNA.
DR EMBL; AACB03000002; KAE8303537.1; -; Genomic_DNA.
DR RefSeq; XP_001708355.1; XM_001708303.1.
DR AlphaFoldDB; E2RTQ4; -.
DR STRING; 184922.E2RTQ4; -.
DR EnsemblProtists; EDO80681; EDO80681; GL50803_7309.
DR GeneID; 5701266; -.
DR KEGG; gla:GL50803_007309; -.
DR VEuPathDB; GiardiaDB:GL50803_7309; -.
DR HOGENOM; CLU_951379_0_0_1; -.
DR InParanoid; E2RTQ4; -.
DR OMA; EEVHANQ; -.
DR Proteomes; UP000001548; Chromosome 4.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0048278; P:vesicle docking; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF427; SYNTAXIN-22-RELATED; 1.
DR Pfam; PF05739; SNARE; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..259
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 98..201
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 19..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 293 AA; 32515 MW; A536B1356947F957 CRC64;
MENMYDDFID EPNDSQSLLP VEKPATGKTA TSSGTSPVPK EILTAYEAIN SAIKRVDDAI
VSLSEATRKA ESINTEVELK EFKNTINGKV AEIKGRMLRE VTESIKDLGK QQAALQRKGA
LDDAQSVIIA GKKRSYQQTV ANKETQLDSI MKKLTHLLDN IGNKIRAAQY DAQRPAGEAE
NEKAEEQMLR QELQEMELVD EREGELIQNI HRDVAEVLAM MGLMAEEVHA NQETINRIEA
NVKAADDDVE AGVEHLKKAE KHHKCSKKCL IIWGVIIAVI AIIVISVLST IFK
//
