ID E2S805_9ACTN Unreviewed; 578 AA.
AC E2S805;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=AMP-binding enzyme {ECO:0000313|EMBL:EFQ84821.1};
GN ORFNames=HMPREF0063_10162 {ECO:0000313|EMBL:EFQ84821.1};
OS Aeromicrobium marinum DSM 15272.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=585531 {ECO:0000313|EMBL:EFQ84821.1, ECO:0000313|Proteomes:UP000003111};
RN [1] {ECO:0000313|EMBL:EFQ84821.1, ECO:0000313|Proteomes:UP000003111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15272 {ECO:0000313|EMBL:EFQ84821.1,
RC ECO:0000313|Proteomes:UP000003111};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ84821.1}.
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DR EMBL; ACLF03000001; EFQ84821.1; -; Genomic_DNA.
DR RefSeq; WP_007076729.1; NZ_CM001024.1.
DR AlphaFoldDB; E2S805; -.
DR STRING; 585531.HMPREF0063_10162; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_7_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000003111; Chromosome.
DR CDD; cd04433; AFD_class_I; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003111}.
FT DOMAIN 32..434
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 486..562
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 578 AA; 63032 MW; FF02962ED30AD121 CRC64;
MTMARGLHPA DKVEDYCAKG WWSDETVDQL FAQQVAARGD ELAVVDPANR AALSGAAPRR
LTWSELDAES THLAARLLNL GLRRGDVLGV QVPNTIELVE AYVAAWMIGV IVSPLPMQYR
EREIVGMANQ AEFAAYLTVA SFGDRSPVTE VHEAREQMPS LRTVIAFGPA EEAAGGLPDG
VLHLAPTPVA ADDRAAVEAH VAADPNDPND CLTICWTSGT ESEPKGVPRC HYDWIAVSWA
TVELPSITSD DVLLNPFPMV NMAGINGMFL PWLRTGCVLV QHHPFDLMTF LQQIAVERVT
YTVAPPALLW TLLHNEALLA KADLSSLTRV GSGSVPLQPV MVRGWQEKFG IGVINFFGSN
EGIGLLSGPE DFPDPDERAQ FFPRYGTPGV KWSGRISEWM HVRLVDVVTG EDITEPGHSG
ELRISGPSVF AGYLNGDQRP SPFDEQGYLK TGDLFEIAGD KNQYLHYLDR AKDLIIRGGM
NIAPVELEGL IGDHPAVVDV AVIGDPDEVL GERIAAIVTL APDAELTLEE LVEFLRGKKI
ASFKLPERLE VRDEMPRNPV GKILKRELRS SHPEGASA
//
