ID   E2S8F9_9ACTN            Unreviewed;       920 AA.
AC   E2S8F9;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   RecName: Full=LTD domain-containing protein {ECO:0000259|PROSITE:PS51841};
GN   ORFNames=HMPREF0063_10316 {ECO:0000313|EMBL:EFQ84464.1};
OS   Aeromicrobium marinum DSM 15272.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Aeromicrobium.
OX   NCBI_TaxID=585531 {ECO:0000313|EMBL:EFQ84464.1, ECO:0000313|Proteomes:UP000003111};
RN   [1] {ECO:0000313|EMBL:EFQ84464.1, ECO:0000313|Proteomes:UP000003111}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15272 {ECO:0000313|EMBL:EFQ84464.1,
RC   ECO:0000313|Proteomes:UP000003111};
RA   Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA   Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA   Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA   Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA   Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA   Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA   Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA   Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA   Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA   Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA   Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA   Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA   Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA   Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA   Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFQ84464.1}.
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DR   EMBL; ACLF03000002; EFQ84464.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2S8F9; -.
DR   STRING; 585531.HMPREF0063_10316; -.
DR   eggNOG; COG3204; Bacteria.
DR   HOGENOM; CLU_011069_0_0_11; -.
DR   Proteomes; UP000003111; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1260; Lamin Tail domain; 4.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   InterPro; IPR036415; Lamin_tail_dom_sf.
DR   InterPro; IPR011041; Quinoprot_gluc/sorb_DH.
DR   Pfam; PF00932; LTD; 4.
DR   SUPFAM; SSF74853; Lamin A/C globular tail domain; 4.
DR   SUPFAM; SSF50952; Soluble quinoprotein glucose dehydrogenase; 1.
DR   PROSITE; PS51841; LTD; 4.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003111};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..920
FT                   /note="LTD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003163886"
FT   TRANSMEM        891..912
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          18..122
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   DOMAIN          137..253
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   DOMAIN          271..385
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   DOMAIN          403..513
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
SQ   SEQUENCE   920 AA;  93664 MW;  3DF6D3B93BDFC2D8 CRC64;
     MGLLACVSLL APVGVLTASP AAAAPADIVI NEIESNGDTT DWIELTNTGV EPVDVSGWIL
     KDDDDSRTLA VAAGTTIEPG GFLAVDVDVD GVPGEFGLGG TDTARVFLPD GTTLIDEHAY
     AGHALTTYGR CPDGTGDFIT TTSSTKGTAN DCTPRVPDVV VNEVESNGDT TDWIELRNNS
     AFPADVSGWI LKDDDDSRTL AIAGGTTIPV GGYLAVDVNV DTTPGTFGLG GTDTARVFLP
     DGTTLIDEYA YVGHAATTYG RCPDGTGDFV VTTSSTKSAA NDCPAGSVPS IVVNEVESNG
     DATDWIELLN TGAAPVDVSG WIVKDNDDGR TLAIAGGTIV PAGGYLAVDT DLDSLPNGFG
     LGNNDSARIF LPDGTTLIAE YSWTGHAATS YGRCPDGTGE FVTTTSTTRA AANDCGPAVR
     INEVESNGDA TDWIELVNNG VTPVDVSGWI LKDDDDSRTL AIAGGTTIAA GGHLAVDVDV
     DGVPGEFGLG GADSARVFLP DGTTLVDEYA WLTHAATTYG RCPDGTGEFA TTQVSTKGAV
     NQCVGDLVTV PFPGSPDVTA VDVPGTFPTN LSGLAYEAAA SVADDSLWAV VNGPGTLHRL
     TSTGGVWDPV DTWTLRYPDG TGDVDAEGVA LTAAGSAGGV YVASERNNDG GGSRLSVLRY
     DVSGGGPDLA ATREWNLTAD LPVVAANAGF EGIAWIPDAD LVAGGFVDES TGVAYDPADY
     PGHGSGVFFL GVEAGGTVYA YVLGDGGAFA RVATIDSGFG SVMELEYEPA SRGLWAVCDD
     TCDGRSTILT LTDGAFGADE VQERPAGLPN VNHEGFAIAP ESRCVDGLKP AFWSDDNGTD
     GRALREGAVR CLGDAGVTPP VVDTGDTGVG GGAPGGLATV IGSLPVVGSQ VPLTVLFGLL
     LLPVGVAIAV AAHRRREGAQ
//