ID   E2X5C8_SHIDY            Unreviewed;       886 AA.
AC   E2X5C8;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 59.
DE   SubName: Full=Acetyl-CoA synthetase {ECO:0000313|EMBL:AHA66631.1};
DE            EC=6.2.1.13 {ECO:0000313|EMBL:AHA66631.1};
GN   ORFNames=Asd1617_03804 {ECO:0000313|EMBL:AHA66631.1};
OS   Shigella dysenteriae 1617.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=754093 {ECO:0000313|EMBL:AHA66631.1, ECO:0000313|Proteomes:UP000031647};
RN   [1] {ECO:0000313|EMBL:AHA66631.1, ECO:0000313|Proteomes:UP000031647}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1617 {ECO:0000313|EMBL:AHA66631.1,
RC   ECO:0000313|Proteomes:UP000031647};
RA   Aksomboon Vongsawan A., Kapatral V., Vaisvil B., Serichantalergs O.,
RA   Hale T.L., Mason C.J.;
RT   "Comparative genomics of Sd1617 to representative strains in evaluating its
RT   pathogenesis.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP006736; AHA66631.1; -; Genomic_DNA.
DR   RefSeq; WP_000082955.1; NZ_ADUT01000017.1.
DR   AlphaFoldDB; E2X5C8; -.
DR   KEGG; sdz:Asd1617_03804; -.
DR   PATRIC; fig|754093.4.peg.3700; -.
DR   HOGENOM; CLU_007415_0_2_6; -.
DR   Proteomes; UP000031647; Chromosome.
DR   GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   Pfam; PF13380; CoA_binding_2; 1.
DR   Pfam; PF13607; Succ_CoA_lig; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:AHA66631.1}.
SQ   SEQUENCE   886 AA;  97859 MW;  6333913F1E044FE0 CRC64;
     MSQRGLEALL RPKSIAVIGA SMKPNRAGYL MMRNLLAGGF NGPVLPVTPA WKAVLGVLAW
     PDIASLPFTP DLAVLCTNAS RNLALLEELG EKGCKTCIIL SAPASQHEDL RACALRHNMR
     LLGPNSLGLL APWQGLNASF SPVPIKRGKL AFISQSAAVS NTILDWAQQR EMGFSYFIAL
     GDSLDIDVDE LLDYLARDSK TSAILLYLEQ LSDARRFVSA ARSASRNKPI LVIKSGRSPA
     AQRLLNTTAG MDPAWDAAIQ RAGLLRVQDT HELFSAVETL SHMRPLRGDR LMIISNGAAP
     AALALDALWS RNGKLATLSE ETCQKLRDAL LGHVAISNPL DLRDDASSEH YVKTLDILLH
     SQDFDALMVI HSPSAAAPAT ESAQALIEAV KHHPRSKYVS LLTNWCGEHS SQEARRLFSE
     AGLPTYRTPE GTITAFMHMV EYRRNQKQLR ETPALPSNLT SNTAKAHLLL QQAIAEGATS
     LDTHEVQPIL QAYGMNTLPT WIASDSTEAV HIAEQIGYPV ALKLRSPDIP HKSEVQGVML
     YLRTANEVQQ AANAIFDRVK MTWPQARVHG LLVQSMANRA GAQELRVVVE HDPVFGPLIM
     LGEGGVEWRP EDQAVVALPP LNMNLARYLV IQGIKSKKIR ARSALRPLDV AGLSQLLVQV
     SNLIVDCPEI QRLDIHPLLA SGSEFTALDV TLDIAPFEGD NESRLAVRPY PHQLEEWVEL
     KNGERCLFRP ILPEDEPQLQ QFISRVTKED LYYRYFSEIN EFTHEDLANM TQIDYDREIA
     FVAVRRIDQT EEILGVTRAI SDPDNIDAEF AVLVRSDLKG LGLGRRLMEK LITYTRDHGL
     QRLNGITMPN NRGMVALARK LGFNVDIQLE EGSVGLTLNL AQREES
//