ID   E2X8W1_SHIDY            Unreviewed;       694 AA.
AC   E2X8W1;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=4-alpha-glucanotransferase {ECO:0000256|ARBA:ARBA00020295, ECO:0000256|RuleBase:RU361207};
DE            EC=2.4.1.25 {ECO:0000256|ARBA:ARBA00012560, ECO:0000256|RuleBase:RU361207};
DE   AltName: Full=Amylomaltase {ECO:0000256|ARBA:ARBA00031423, ECO:0000256|RuleBase:RU361207};
DE   AltName: Full=Disproportionating enzyme {ECO:0000256|ARBA:ARBA00031501, ECO:0000256|RuleBase:RU361207};
GN   ORFNames=Asd1617_04837 {ECO:0000313|EMBL:AHA67664.1};
OS   Shigella dysenteriae 1617.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=754093 {ECO:0000313|EMBL:AHA67664.1, ECO:0000313|Proteomes:UP000031647};
RN   [1] {ECO:0000313|EMBL:AHA67664.1, ECO:0000313|Proteomes:UP000031647}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1617 {ECO:0000313|EMBL:AHA67664.1,
RC   ECO:0000313|Proteomes:UP000031647};
RA   Aksomboon Vongsawan A., Kapatral V., Vaisvil B., Serichantalergs O.,
RA   Hale T.L., Mason C.J.;
RT   "Comparative genomics of Sd1617 to representative strains in evaluating its
RT   pathogenesis.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC         position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC         glucan.; EC=2.4.1.25; Evidence={ECO:0000256|ARBA:ARBA00000439,
CC         ECO:0000256|RuleBase:RU361207};
CC   -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC       {ECO:0000256|ARBA:ARBA00005684, ECO:0000256|RuleBase:RU361207}.
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DR   EMBL; CP006736; AHA67664.1; -; Genomic_DNA.
DR   RefSeq; WP_000444321.1; NZ_ADUT01000021.1.
DR   AlphaFoldDB; E2X8W1; -.
DR   KEGG; sdz:Asd1617_04837; -.
DR   PATRIC; fig|754093.4.peg.4703; -.
DR   HOGENOM; CLU_022072_1_1_6; -.
DR   Proteomes; UP000031647; Chromosome.
DR   GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR003385; Glyco_hydro_77.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR048458; MalQ_N.
DR   NCBIfam; TIGR00217; malQ; 1.
DR   PANTHER; PTHR32438; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR   PANTHER; PTHR32438:SF5; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR   Pfam; PF02446; Glyco_hydro_77; 1.
DR   Pfam; PF21226; MalQ_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU361207};
KW   Glycosyltransferase {ECO:0000256|RuleBase:RU361207,
KW   ECO:0000313|EMBL:AHA67664.1};
KW   Transferase {ECO:0000256|RuleBase:RU361207, ECO:0000313|EMBL:AHA67664.1}.
FT   DOMAIN          53..128
FT                   /note="MalQ N-terminal beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF21226"
SQ   SEQUENCE   694 AA;  78516 MW;  E0C5BF20600B99AF CRC64;
     MESKRLDNAA LAAGISPNYI NAHGKPQSIS AETKRRLLDA MHQRTATKVA VTPVPNVMVY
     TSGKKMPMVV EGSGEYSWLL TTEEGTQYKG HITGGKAFNL PTKLPEGYHT LTLTQEDQRA
     HCRVIVAPKR CYEPQALLNK QKLWGACVQL YTLRSEKNWG IGDFGDLKAM LVDVAKRGGS
     FIGLNPIHAL YPANPESASP YSPSSRRWLN VIYIDVNAVE DFHLSEEAQA WWQLPTTQQT
     LQQARDADWV DYSTVTALKM TALRMAWKGF AQRDDEQMAA FRQFVADQGD SLFWQAAFDA
     LHAQQVKEDE MRWGWPAWPE MYKNVDSPEV RQFCEEHRDD VDFYLWLQWL AYSQFAACWE
     ISQGYEMPIG LYRDLAVGVA EGGAETWCDR ELYCLKASVG APPDILGPLG QNWGLPPMDP
     HIITARAYEP FIELLRANMQ NCGALRIDHV MSMLRLWWIP YGETADQGAY VHYPVDDLLS
     ILALESKRHR CMVIGEDLGT VPVEIVGKLR SSGVYSYKVL YFENDHEKTF RAPKAYPEQS
     MAVAATHDLP TLRGYWESGD LTLGKTLGLY PDEVVLRGLY QDRELAKQGL LDALHKYGCL
     PKRAGHKASL MSMTPTLNRG LQRYIADSNS ALLGLQPEDW LDMAEPVNIP GTSYQYKNWR
     RKLSATLETM FADDGVNKLL KDLDRRRRAA AKKK
//