ID   E2ZIS9_9FIRM            Unreviewed;       269 AA.
AC   E2ZIS9;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:EFQ06978.1};
DE            EC=3.5.1.28 {ECO:0000313|EMBL:EFQ06978.1};
GN   ORFNames=HMPREF9436_01574 {ECO:0000313|EMBL:EFQ06978.1};
OS   Faecalibacterium cf. prausnitzii KLE1255.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=748224 {ECO:0000313|EMBL:EFQ06978.1, ECO:0000313|Proteomes:UP000006028};
RN   [1] {ECO:0000313|EMBL:EFQ06978.1, ECO:0000313|Proteomes:UP000006028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KLE1255 {ECO:0000313|EMBL:EFQ06978.1,
RC   ECO:0000313|Proteomes:UP000006028};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFQ06978.1}.
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DR   EMBL; AECU01000120; EFQ06978.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2ZIS9; -.
DR   STRING; 748224.HMPREF9436_01574; -.
DR   eggNOG; COG0860; Bacteria.
DR   HOGENOM; CLU_014322_9_5_9; -.
DR   BioCyc; FCF748224-HMP:GTSS-256-MONOMER; -.
DR   Proteomes; UP000006028; Unassembled WGS sequence.
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR   CDD; cd02696; MurNAc-LAA; 1.
DR   Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR   InterPro; IPR002508; MurNAc-LAA_cat.
DR   PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR   PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR   Pfam; PF01520; Amidase_3; 1.
DR   SMART; SM00646; Ami_3; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EFQ06978.1}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..269
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003166146"
FT   DOMAIN          112..251
FT                   /note="MurNAc-LAA"
FT                   /evidence="ECO:0000259|SMART:SM00646"
SQ   SEQUENCE   269 AA;  29324 MW;  6752352B56FCCCE0 CRC64;
     MLKNTVILLF CAVSIWFGSS LWHAALTLQT AQPAESIAGE EFRPQVGDPP YRVVIDAGHG
     GADPGARGVI EEKDMTAATA SELIRLLQQD SNFIPLQTRD SFDETTTPAQ RAARADEQAP
     QLLLSIHGNS TANGSTASGF ECYPAVPGRT WHQESFYFAQ LLAKGMQAAG ASLRGRGGVR
     YIYYLENDQK QLVESTHTEV RAERSFTLLE DVNCPAVLAE QCFVTNEADV AQFGSEEGCK
     KTARVYYEAI CAYFGTQPQA EQLAGFTLN
//