ID E3CSI8_STRVE Unreviewed; 388 AA.
AC E3CSI8;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=HMPREF9192_0164 {ECO:0000313|EMBL:EFQ58612.1};
OS Streptococcus vestibularis F0396.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=904306 {ECO:0000313|EMBL:EFQ58612.1, ECO:0000313|Proteomes:UP000004896};
RN [1] {ECO:0000313|EMBL:EFQ58612.1, ECO:0000313|Proteomes:UP000004896}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0396 {ECO:0000313|EMBL:EFQ58612.1,
RC ECO:0000313|Proteomes:UP000004896};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ58612.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEKO01000009; EFQ58612.1; -; Genomic_DNA.
DR AlphaFoldDB; E3CSI8; -.
DR eggNOG; COG0116; Bacteria.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000004896; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 45..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 388 AA; 43704 MW; BAAB0BE27A3497B1 CRC64;
MKETFTLVAT AAAGLEAVVG RELRELGYEI QVENGKVRFQ GDVRAIAETN LWLRAADRIK
IVVGEFPART FEELFQGVYA LDWENYLPLG AKFPISKAKC VKSKLHNEPS VQAISKKAVV
KKLQKYFHRP EGVPLQETGA EFKIEVSILK DKATALIDTT GASLFKRGYR TDKGGAPIKE
NMAAAILELS NWYPDKPLID PTCGSGTFCI EAAMIGMNIA PGFNRDFAFE AWNWVDKDLV
QSVRDEADSK ANYDVELDIM GCDIDSRMVE IAKANAREAG LEDVVKLKQM RLQDLKTDKI
NGVIISNPPY GERLLDDKAV DILYNEMGQT FAPLKTWSKF ILTSDEQFES KYGMKADKKR
KLYNGTLRVD LYQYFGERVR RSEARKVN
//
