ID E3HDH4_ILYPC Unreviewed; 761 AA.
AC E3HDH4;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ADO84160.1};
GN OrderedLocusNames=Ilyop_2401 {ECO:0000313|EMBL:ADO84160.1};
OS Ilyobacter polytropus (strain ATCC 51220 / DSM 2926 / LMG 16218 / CuHBu1).
OG Plasmid pILYOP01 {ECO:0000313|EMBL:ADO84160.1,
OG ECO:0000313|Proteomes:UP000006875}.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Ilyobacter.
OX NCBI_TaxID=572544 {ECO:0000313|EMBL:ADO84160.1, ECO:0000313|Proteomes:UP000006875};
RN [1] {ECO:0000313|EMBL:ADO84160.1, ECO:0000313|Proteomes:UP000006875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51220 / DSM 2926 / LMG 16218 / CuHBu1
RC {ECO:0000313|Proteomes:UP000006875};
RC PLASMID=pILYOP01 {ECO:0000313|Proteomes:UP000006875};
RX PubMed=21304735; DOI=10.4056/sigs.1273360;
RA Sikorski J., Chertkov O., Lapidus A., Nolan M., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Brambilla E., Yasawong M.,
RA Rohde M., Pukall R., Spring S., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Ilyobacter polytropus type strain (CuHbu1).";
RL Stand. Genomic Sci. 3:304-314(2010).
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DR EMBL; CP002282; ADO84160.1; -; Genomic_DNA.
DR RefSeq; WP_013388819.1; NC_014633.1.
DR AlphaFoldDB; E3HDH4; -.
DR KEGG; ipo:Ilyop_2401; -.
DR HOGENOM; CLU_000445_70_44_0; -.
DR Proteomes; UP000006875; Plasmid pILYOP01.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd01948; EAL; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Plasmid {ECO:0000313|EMBL:ADO84160.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006875};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..275
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 360..494
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 502..755
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 761 AA; 88196 MW; 956C7367DE1503DE CRC64;
MSIGGSDIYV SNLDLNIEHK KIEMPHLPVM RFSSPVENNK GKTIGILIIN FKGFKFLDTF
RNYLKINNPL IQISLTDSNG YYLYNKDESK NFGFMFEGEA KNYRLENESP KLWEMINSSS
EKNFETKDKV LYFKKIDPEF KGHIYFDNEN FYWNVVASLK KEDLPKLYPD IFIFKKNIKL
YILLGILALS ATIITLLHLK KRESNQLYMA ELILGYVDEA VLITDSAGNI LDFNDEFLNF
TDLDKDEILK SDTSLFELNV THPEIYDDIK KEMNKGKKWA GELWLKKKDN SKYPAILTIN
NVANPKNKNT EHYVCVIKDL TSEKQREAEI EYLLTHHSKT KLPNENLMRQ LIDEEIKNNS
GFSLIYIKLK NYNDLEIKYT DEFLNLIYEN IIGKIESIVS EKENIAHLST DTFIAICKTS
TNKLLLNKSM IELFKGLKSS ITIKDISVHL EFEMGSVIFP EHGDSSRELL KKALFSIRAL
KFHPERNYII YHNNIEKSVR RELEIEENIV SAIENNEFQV YFQPQIDSNT ETINGLEALI
RWNNTTLGNV SPMEFIPLAE EKGIINKIDM WVVEEVARLT KKLGLHEQKG IKISINLSAN
DFKNDFLVED VVAILDFHGL DHNQFEVELT EGTLISDHEY VSTKLEEFKS YGITVAIDDF
GTGFSSMSYL KKLNFDKLKI DRSFIKDYPK MDNGSIAEVI SYLAQKLKVN LIAEGVETVE
QLKYLQSIGC VNIQGYYYSK PLSEKELKIY LKEHFEKKRL S
//
