ID E3I0X5_RHOVT Unreviewed; 494 AA.
AC E3I0X5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=tRNA threonylcarbamoyladenosine biosynthesis protein TsaE {ECO:0000256|ARBA:ARBA00019010};
DE AltName: Full=t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE {ECO:0000256|ARBA:ARBA00032441};
GN OrderedLocusNames=Rvan_3095 {ECO:0000313|EMBL:ADP72298.1};
OS Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG
OS 4299).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Rhodomicrobium.
OX NCBI_TaxID=648757 {ECO:0000313|EMBL:ADP72298.1, ECO:0000313|Proteomes:UP000001399};
RN [1] {ECO:0000313|Proteomes:UP000001399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299
RC {ECO:0000313|Proteomes:UP000001399};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- SIMILARITY: Belongs to the TsaE family.
CC {ECO:0000256|ARBA:ARBA00007599}.
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DR EMBL; CP002292; ADP72298.1; -; Genomic_DNA.
DR AlphaFoldDB; E3I0X5; -.
DR STRING; 648757.Rvan_3095; -.
DR KEGG; rva:Rvan_3095; -.
DR eggNOG; COG0802; Bacteria.
DR eggNOG; COG3178; Bacteria.
DR HOGENOM; CLU_021467_2_1_5; -.
DR OrthoDB; 9809275at2; -.
DR Proteomes; UP000001399; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0002949; P:tRNA threonylcarbamoyladenosine modification; IEA:InterPro.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003442; T6A_TsaE.
DR NCBIfam; TIGR00150; T6A_YjeE; 1.
DR PANTHER; PTHR33540:SF1; N-ACETYLMURAMATE_N-ACETYLGLUCOSAMINE KINASE; 1.
DR PANTHER; PTHR33540; TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE; 1.
DR Pfam; PF01636; APH; 1.
DR Pfam; PF02367; TsaE; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001399};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 163..418
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 494 AA; 54444 MW; 6AFC5D5964074CE9 CRC64;
MWEIDSAEAL QALASRLSAF VSERDAITLA GDLGAGKTTF AQGLLSALGV TEAATSPTYQ
IVHAYETPRR TVYHCDLYRL HPGDEEEIGF AEMCQTGAVV VEWPDIVADV LPHDRLDVRI
EGEGGTRRVT LTGFGAWEKK LARFRQIEAF LARCGWEGAR CLGLRGDASA RQFMRLLRAG
ETAMLMDWPT QSDGPPIRDG RPYCAIAHLA REGTPFIAVS HWLREHAGLS APAVTASDKD
AGLYLVEDLG DAVFGDLIAG GEPLEPLYAL AVDGLSAVRA SGVPRSLPGP GGGLYDVPAF
DREAMDVELD LLLQWYFRLE PVAADPAEMA RSFVEAWSPH LDWLDKQPKT IALRDYHSPN
LLLCRERDGL KRLGVIDFQD AVWTHPAYDL VSLLQDARLD VPEAVEHALY ARYCEAAAAA
DPAFNAAAFA RAYAILGAER NTKILGIFAR LSMRDGKHVY LAHLPRIRRY LWRNLAHPAL
GELKAWYEAH LHKA
//
