ID   E3LK49_CAERE            Unreviewed;      1192 AA.
AC   E3LK49;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN   ORFNames=CRE_18416 {ECO:0000313|EMBL:EFO99917.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268410; EFO99917.1; -; Genomic_DNA.
DR   RefSeq; XP_003115430.1; XM_003115382.1.
DR   AlphaFoldDB; E3LK49; -.
DR   STRING; 31234.E3LK49; -.
DR   EnsemblMetazoa; CRE18416.1; CRE18416.1; WBGene00062061.
DR   eggNOG; KOG4177; Eukaryota.
DR   HOGENOM; CLU_002600_0_0_1; -.
DR   InParanoid; E3LK49; -.
DR   OMA; HIWMDDA; -.
DR   OrthoDB; 2883182at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR003125; WSN.
DR   PANTHER; PTHR22956; ANKYRIN REPEAT-CONTAINING PROTEIN F37A4.4-RELATED-RELATED; 1.
DR   PANTHER; PTHR22956:SF14; BRCT DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF02206; WSN; 1.
DR   SMART; SM00248; ANK; 2.
DR   SMART; SM00292; BRCT; 1.
DR   SMART; SM00453; WSN; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52113; BRCT domain; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
DR   PROSITE; PS50172; BRCT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        790..817
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REPEAT          886..918
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          1002..1055
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   COILED          617..647
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1192 AA;  138038 MW;  53A64C84D850EE8C CRC64;
     MISEQSNLKL IAEDFRILAR VTNAIFLHNA ALNRQIQVDD VVSELFQISK ERFNAIINVD
     VKTAIPEIKR MKKNKWTPTH NSQNFTSYLM PQISKIYSDL PENMKKLKRV GSISSDELLI
     EAAAVRTKDI FNTTCSRLDF ENMKKFRMLF AGQPDNYQIP ENNEIEEILK TFKSQSMKVI
     ECMKGLKDLE VKLRQQSIIK AYNRYKTVQK VKKIVMDFEI AQNSAGLWGN ALDTLKSYFN
     STNDVASTSM SGTNATQFLE KMSIVMDQVN QSVWTTEYHT YDYTDTDLTF TAGFRDSSDL
     LKVFQDLRSP WFQKKIARGA STAKLIKALQ PYRNISQMII NLETEWNLMM DFSEQKIDTD
     VLNGVSVLKN IKTFAAKSTK HLKLLENIKG KIIQCQSFGT KVFDSSAFIR FEKEQQPGEK
     VMNQLAKLSK HISDVSSKLM RESNLFETRL IYNEQILSVL SGVNGNFNDS FKIVKETEVL
     IDSFGDKSSR FYDFIGNIAS VSEELNHLRV LSENVTSVTT TFGIHKVLES SKILAVAECF
     RDHVDELKET KQILEIQQHI LNFPKNYIMD KIIKYLKKLS KVRLEMKNIG KLVLALRKVN
     QNQRNKTDNH VLTLKNSKSL SENLGQSTKV LEDLEEARRN REEFRKNSKF SSNVVAIIGR
     QGLADWMKPM NRFDLLLKEA DQLDREAKES RNATLIEMTD IFEKATKIHG IVGSKDLLNK
     VFEELEIHYP EDEKDAMEFF QLIRNLDLDF SKHQARLKNV RVTVTSLKQY FDEIFGHIKP
     KTVTIEIKPA VSWIVILSIS IGFFFFVIIG VFAVYGLTES GRTKYKNWYL YYFGKHADFE
     KRWRYSNFMD TTDGKNALLD AVREGNRANL LKVLKNGAYI DAYNKFGNTS LHVATKFAHP
     DLVELLIKYG ADRSLLNYKN RTPVQMIPHD YKTAYPERIE KYEQIMGIYE KYEKKSFRIA
     VPREFPDSSF HIWMDDATDE KLCNKFMDKF RAITSDEALP TTTHCVVRVD TNGILETSHL
     DLFMWIFHGV IIVKEQWMTD CLENEKVIME DEKYLVEKVK FNGVVYNSIL PWTEYMAKGE
     MPYLIGVFVA VTIPDYKNLL TLSTIVTNQG GVMMSTFPLK EQFNRNSHPY LHAHLGPLFL
     IHDGTIDLSV YKNDKDKMYT LFTEEEFIVF MLKRNINRDN RENPIPVMIN DE
//