ID E3LKU1_CAERE Unreviewed; 302 AA.
AC E3LKU1;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Pre-mRNA-splicing factor 38 {ECO:0000256|RuleBase:RU367025};
GN ORFNames=CRE_18486 {ECO:0000313|EMBL:EFO99798.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for pre-mRNA splicing.
CC {ECO:0000256|RuleBase:RU367025}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367025}.
CC -!- SIMILARITY: Belongs to the PRP38 family.
CC {ECO:0000256|ARBA:ARBA00006164, ECO:0000256|RuleBase:RU367025}.
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DR EMBL; DS268410; EFO99798.1; -; Genomic_DNA.
DR RefSeq; XP_003115311.1; XM_003115263.1.
DR AlphaFoldDB; E3LKU1; -.
DR STRING; 31234.E3LKU1; -.
DR EnsemblMetazoa; CRE18486.1; CRE18486.1; WBGene00062174.
DR GeneID; 9839153; -.
DR KEGG; crq:GCK72_019151; -.
DR CTD; 9839153; -.
DR eggNOG; KOG2888; Eukaryota.
DR HOGENOM; CLU_034151_0_0_1; -.
DR InParanoid; E3LKU1; -.
DR OMA; NVKESYY; -.
DR OrthoDB; 242061at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR InterPro; IPR005037; PRP38.
DR PANTHER; PTHR23142:SF2; PRE-MRNA-SPLICING FACTOR 38B; 1.
DR PANTHER; PTHR23142; UNCHARACTERIZED; 1.
DR Pfam; PF03371; PRP38; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|RuleBase:RU367025};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|RuleBase:RU367025};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367025};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728, ECO:0000256|RuleBase:RU367025}.
FT REGION 28..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..302
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 302 AA; 35121 MW; 4750A30BE68C0C47 CRC64;
MDTVQAIIQQ QIEAGTFLQS VQQGQQVQQE QTNYGEEDEY EDEEGTYKGK RSNTLPIWGN
QVTMNLNTLV LENIRESYYY KNNLVEIDSF QTLVEQIFYQ VKHLEPWEKG TRRLQGMTGM
CGGVRGVGAG GVVSSAYCLL YRLFNLRISR KQLISMLNSR QSVYIRGIGF MYIRYTQPPA
DLWYWLEPYL DDDSEIDPRS GGGDLMTFGQ MVRTMINKLD WYGTLFPRIP VPIQKEIDER
FAERKKKQLR EEDEWQGESS EKPAEDGEGI GKVLPKVSKC KHHLRHHHCR KHRKNCPAKA
KR
//
