ID   E3LRS8_CAERE            Unreviewed;       687 AA.
AC   E3LRS8;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 57.
DE   SubName: Full=CRE-FEH-1 protein {ECO:0000313|EMBL:EFP09147.1};
GN   Name=Cre-feh-1 {ECO:0000313|EMBL:EFP09147.1};
GN   ORFNames=CRE_25186 {ECO:0000313|EMBL:EFP09147.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268414; EFP09147.1; -; Genomic_DNA.
DR   RefSeq; XP_003112893.1; XM_003112845.1.
DR   AlphaFoldDB; E3LRS8; -.
DR   STRING; 31234.E3LRS8; -.
DR   EnsemblMetazoa; CRE25186.1; CRE25186.1; WBGene00054882.
DR   GeneID; 9825244; -.
DR   KEGG; crq:GCK72_009659; -.
DR   CTD; 9825244; -.
DR   eggNOG; ENOG502QT08; Eukaryota.
DR   HOGENOM; CLU_021196_2_0_1; -.
DR   InParanoid; E3LRS8; -.
DR   OMA; TRRFMCH; -.
DR   OrthoDB; 5404780at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0005884; C:actin filament; IEA:EnsemblMetazoa.
DR   GO; GO:0001540; F:amyloid-beta binding; IEA:EnsemblMetazoa.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:EnsemblMetazoa.
DR   GO; GO:0007631; P:feeding behavior; IEA:EnsemblMetazoa.
DR   GO; GO:0002119; P:nematode larval development; IEA:EnsemblMetazoa.
DR   CDD; cd01272; PTB1_Fe65; 1.
DR   CDD; cd01271; PTB2_Fe65; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039576; APBB1/2/3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR   PANTHER; PTHR14058:SF8; PROTEIN FE65 HOMOLOG; 1.
DR   Pfam; PF00640; PID; 2.
DR   SMART; SM00462; PTB; 2.
DR   SMART; SM00456; WW; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS01179; PID; 2.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT   DOMAIN          232..265
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          351..477
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          520..636
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          19..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          87..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..231
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        264..285
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   687 AA;  78535 MW;  4F8968CC902BF34C CRC64;
     MREGTPRVRI EVNKRPTHFV SESEEQRLQR VHSRDSDTAT MNFVTDDRMQ EEHEEYSAFK
     EAYEEEESRE YVIENGVKRL VNQHYDSRGY SSAGRGQKGR REEERRRNMA VDYSSQDFRQ
     SLAAIDQASR DGAISRGEDG VRVRQIGDTT IMTEHRDPYS FYWQLDQQRR EAESPPRRAP
     PTDYVIDEEE EVLDTVLSPE TDDSGVMFEN QYRRPVRHPL PPPPPIMEEE PKDLPPGWEK
     HQDPQGYSYY WHVDSGTIQR QPPPPVRDVT PARSPSPPPP PPVYSVTTAS RETQADAPPP
     QIIQLPPQQP VIEEHAFKQT TTKRRIEQDE MSEGYAEENQ IENGDSYHKP VRFAVRSMGW
     IEISEDELTA EKSSRAVNSC IVELTNRTDI DNIPKWGDGR ELIMELDDNE LALIDPDSMN
     VIHAERIQSI RVWGVGRDNG RDFAYVSRDR GTRRFMCHVF RCDTSAKTIA NTLRDICKRL
     MLHRRPSSLH AIESGEKRIV RSEGLSAPID EPRKVLRCHF LGVTQVPKAT GIEILNEAVD
     RLVSQVRPER WIFADVSIAP STIAIVEVNG GQIAECRVRY LSFLGIGKDV KHCAFIMQTS
     NESFMCYVFH VEPSAATMAK MIEAACKLRY QKVLDAHSSS RHHSGMSNHG PLPPPSSYHG
     KGWTETFRDA FGSVTSRMVP SRSTQRL
//