ID   E3LYG3_CAERE            Unreviewed;      1283 AA.
AC   E3LYG3;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   RecName: Full=BPTI/Kunitz inhibitor domain-containing protein {ECO:0000259|PROSITE:PS50279};
GN   ORFNames=CRE_04847 {ECO:0000313|EMBL:EFO86724.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268419; EFO86724.1; -; Genomic_DNA.
DR   RefSeq; XP_003110892.1; XM_003110844.1.
DR   STRING; 31234.E3LYG3; -.
DR   EnsemblMetazoa; CRE04847.1; CRE04847.1; WBGene00055845.
DR   GeneID; 9801080; -.
DR   KEGG; crq:GCK72_010374; -.
DR   CTD; 9801080; -.
DR   eggNOG; KOG4295; Eukaryota.
DR   HOGENOM; CLU_004071_0_0_1; -.
DR   InParanoid; E3LYG3; -.
DR   OMA; CCRREAR; -.
DR   OrthoDB; 2874634at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   CDD; cd00109; Kunitz-type; 1.
DR   CDD; cd22593; Kunitz_conkunitzin; 2.
DR   Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 6.
DR   InterPro; IPR006150; Cys_repeat_1.
DR   InterPro; IPR006149; EB_dom.
DR   InterPro; IPR002223; Kunitz_BPTI.
DR   InterPro; IPR036880; Kunitz_BPTI_sf.
DR   InterPro; IPR028150; Lustrin_cystein.
DR   InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR   PANTHER; PTHR46339; PROTEIN CBG15282-RELATED; 1.
DR   PANTHER; PTHR46339:SF8; PROTEIN CBG18270; 1.
DR   Pfam; PF01683; EB; 2.
DR   Pfam; PF00014; Kunitz_BPTI; 6.
DR   Pfam; PF14625; Lustrin_cystein; 8.
DR   SMART; SM00131; KU; 6.
DR   SMART; SM00289; WR1; 13.
DR   SUPFAM; SSF57362; BPTI-like; 6.
DR   PROSITE; PS00280; BPTI_KUNITZ_1; 2.
DR   PROSITE; PS50279; BPTI_KUNITZ_2; 6.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1283
FT                   /note="BPTI/Kunitz inhibitor domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003173813"
FT   DOMAIN          190..244
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
FT   DOMAIN          299..352
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
FT   DOMAIN          398..451
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
FT   DOMAIN          505..557
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
FT   DOMAIN          611..662
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
FT   DOMAIN          1027..1085
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
SQ   SEQUENCE   1283 AA;  142929 MW;  974FC78538551409 CRC64;
     MIYSLNRITC FLIICIQVSL TFGTIPLSEG LHQIYARNAA DVKKLGDNCT RNTECVSGAV
     CLGTCRCRNT HVSVEEQCWK KVEPGNVGCT FDEQCEGVWP MTTCQSGQCA CAEEETLIET
     PEGNVCVVPG NCPTNNVNGA LYDRATHRVS TCLTFTSKKE KNTQFIGCDE YPEVYDCIAG
     TCCPTRGMTC IQPLSTGETK NSSTNEDERW WYNSESGQCL PFKYSGNGGN SNNFLTKTQC
     ESYCGGRCIR GDPLPLEDSI PPSNDNYFCK IHESDRQLCC PTPSFVCSSL GGVNVDKNTM
     RPFSNGSPRR GAEVLQRWYW DTNELACKTF KYYGQGGNFN NFGEKQECVD FCTAGLCPHG
     SPLNDPSDNI QRCQGQEQCP ETHECKNTIC CPRPAATCLQ TLKTREKCEP GETTTKWTYS
     TEHNMCKSVI ASRCLIGDNQ FESIEECQTV CSSVQAQPKC PIGRAYKGSD QVVVRCSSLK
     RCPSNYECIY TGTVHACCPS RENICNQGLQ VGTTCGMSTL QRWYYDPSHN RCNQFEYQGC
     NGNDNNFVTR LDCIETCHRF DCPDGGEALV DSSNGRVIAC ERNDDCPSTH MCTRQLYSNR
     TSCCPSRKWI CSHDANEGVA CGTPSKRFYF DANTETCLQF TYLGCAGNAN SFSNRVACYQ
     FCQSASCSSS EVVYQPSNLD EPFDCSLKTC PRHFSCVRNV WDETKNVCCG SPNFGVCSST
     QHPMLLFSTQ QPMSCTPNSQ NSCPLSFQCT YSSIRMLYFC CRDIEKIDKC LQGSRPEIWQ
     STAEPRACSR DSQCPSTTSC FAPTPFSSGL CCARIDEICP ATFIYDEQKS SDGQCSPLEK
     NTCGRDGQSV CLYSDVKNRF VCCRREARQI QALAKCPPGS IMELTKTYCD PENPCPKTHF
     CMKKSTDRKG ICCRHPSLKR VMPMKTRKAG ATSRKQTSRY RCPKGEKILK IDGEAKNCEV
     DADCPEFYKC TSQGASSTYQ SICCGLDINE ICPTRVYPAI RVQKCSMCAI GYECHKNYCC
     PQKEVACSQP IPELNNDKDS DESIIRYYYD SETNTCHSFN YLRIIGQSST AQNHFSDHSS
     CIDMCVQSQI SEEDLQCPHP YVNPLDHPQM CITSLKSCSD SETCLKTTTG KNYVCCQHPP
     SFQMLMNNLC GASYQPTLNK SGNPIRCSSS SRCASRICRQ SPVLRYSICC QRRIPKTRLL
     IRPLSEGQIR KPICRSEAES TMGSCLPKLF PGETECEVDS QCVSPSTCNE RRCTCPEGTV
     QFRRMCGNIL VGIMKKKEVT VTG
//