ID E3MA19_CAERE Unreviewed; 626 AA.
AC E3MA19;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=CRE_17083 {ECO:0000313|EMBL:EFO96851.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS268431; EFO96851.1; -; Genomic_DNA.
DR RefSeq; XP_003107011.1; XM_003106963.1.
DR AlphaFoldDB; E3MA19; -.
DR STRING; 31234.E3MA19; -.
DR EnsemblMetazoa; CRE17083.1; CRE17083.1; WBGene00060183.
DR GeneID; 9809523; -.
DR KEGG; crq:GCK72_022251; -.
DR CTD; 9809523; -.
DR eggNOG; KOG3764; Eukaryota.
DR HOGENOM; CLU_028639_1_0_1; -.
DR InParanoid; E3MA19; -.
DR OMA; WIMIHAV; -.
DR OrthoDB; 3037749at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23506; -; 1.
DR PANTHER; PTHR23506:SF26; MFS-TYPE TRANSPORTER SLC18B1; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 224..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 226..625
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 23..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 68026 MW; 3A498C58AC80FC88 CRC64;
MSGTDMPYTF DQDPLDMDTS SEVVYPKVGG YGGTSHQRSG STSAPKAKKV VSINPSDTKK
STQLLKTRNY STSNAVDNEL TPLLHPSVSL PTVVGYDGFS EDYQPGHTAT TTRSEIGQQE
LARKKRRRPR YNTLQAANRR KKPRPFIISP FMPISTQISV DGPRTSVLNA KVNYETAAET
LSIKESEGSE SDSDEESGIS DEEQTVPFLK SALQTVSALS SRQILSISML SLANLCSTIA
FSCIAPFYPA EAKLKNLSET QTGIVFGIFE FTMFIISPIF GKYIILIGAR TMFIVGIAVT
GFTAILFGFL NYLPSGQVFF WFSVLVRILE AVGDAAFVTS SFAIAAKSFP KNVAFVVGIL
ETFAGLGYTA GPVIGGLLYD IGGFQLPFLV LGVVLLVAAV LAFFVIENSK DDETNAEGKG
MLEILKLPQI WLPIFSVISC AISLSFLDPT LSNHLESFKL TPTEIGLMFL LCGGFYTVMC
PVFGAIMDRL HNGSTLLFFG SIATLLSMFF IGPTPLLSGY VEKDLWVIGI SLAVLGLAAS
ALYIPCFQMC LDEVKDKGFD DNFQTYGCVS GIFQAAFGFG SFIGPTFGSV VVESVGFRWT
TTMIAFLHIL LSTVILMRII IKKCRK
//
