GenomeNet

Database: UniProt
Entry: E3MCK6_CAERE
LinkDB: E3MCK6_CAERE
Original site: E3MCK6_CAERE 
ID   E3MCK6_CAERE            Unreviewed;      1794 AA.
AC   E3MCK6;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   25-OCT-2017, entry version 47.
DE   SubName: Full=CRE-NCA-2 protein {ECO:0000313|EMBL:EFO98541.1};
GN   Name=Cre-nca-2 {ECO:0000313|EMBL:EFO98541.1};
GN   ORFNames=CRE_20293 {ECO:0000313|EMBL:EFO98541.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; DS268435; EFO98541.1; -; Genomic_DNA.
DR   RefSeq; XP_003106015.1; XM_003105967.1.
DR   STRING; 31234.CRE20293; -.
DR   EnsemblMetazoa; CRE20293; CRE20293; WBGene00061652.
DR   GeneID; 9807318; -.
DR   CTD; 9807318; -.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   InParanoid; E3MCK6; -.
DR   OMA; MLGDSAM; -.
DR   OrthoDB; EOG091G00F9; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005261; F:cation channel activity; IEA:InterPro.
DR   GO; GO:0040017; P:positive regulation of locomotion; IEA:EnsemblMetazoa.
DR   GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:EnsemblMetazoa.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:EnsemblMetazoa.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028823; NALCN.
DR   PANTHER; PTHR10037:SF214; PTHR10037:SF214; 1.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008281};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     99    120       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    141    163       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    213    235       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    326    346       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    408    439       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    451    475       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    541    565       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    611    634       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    954    978       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    990   1022       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1067   1090       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1180   1207       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1266   1282       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1294   1314       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1334   1356       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1368   1384       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1405   1428       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1489   1515       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       74    363       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      417    639       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      916   1211       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1261   1526       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1794 AA;  207047 MW;  CFBE85AB01CA3BEA CRC64;
     MFCLSACRAA ALSTTMLTRR KSSIDGTKSE RSRRRGESIG GAFTDMINIE PTSIINKSTE
     LLHERFLRDM VRAACLLSMI SLCLHTPETI KMWPPLNYII LVNDVIVTLI FIGEAAVTIN
     QNGLFDNQNS YLRDRWYQFE FFLLINHILS CIIHIYELCS IWFPSLNFVY YPWLGALRSA
     RPFIFLRFIR SIVRFKLPKN RIKSIMKRSS QQIQNVTIFF MFFVFSYAIM GVQLFGRLNY
     HCVVNGTDPN NVTIADLAIP DTMCSQKGAG GYECPGNMVC MRLQLKPQEE GFYGQFSDFA
     SSLFTVYLAA SQEGWVYVLY DCLDSLPSFL AFFYFVTLIF FLAWLVKNVF IAVITETFAE
     IRVQFNEMWQ TREATSDHVY TQKLEKDEDG WKLVEVDKYN RAHSNNSLYL HTIVTSTAFQ
     TVMQLMILAN AIFHATFVFY HDESDQIRKV WYYYVEVGFT ILFNTEVIIK IYAFGWKAYI
     ARGQHKFDCL LCIGSSLNAI WILYETNIFT YFQVFRIARL IKASPMLEDF VYKIFGPGKK
     LGGLVIFTGI LLIVTSAISL QLFCYVPKLN KFTNFAVAFM SMFQIITQEG WTDVVIEILR
     ACNEQAVPFV AIYFVAYHLL VTLFVLSLFV AVILDNLEMD EELKKVKQLK AREQDTIKTT
     LPMRLRIFNR FPTAPTMVTM KKVSSEFPLP KIRDSFTRQF ADEFVETSDD TIQEIGLKVR
     SMLSGKGPSK ETRKTTTIRH VGQLSNKTIL TSMLTESNRN RALFSESNQH LANFTRSNTS
     SKHGKSGILS ANSRSRTRGL ASLKGKNMVE GFKENGDLRP EDTARKVEKH GEIDFKALQM
     KRAHAEITRN RIEEEMRENH PMFDRPLFLV GRESSLRRMC QMIAHSRHSY DQNDGQHRKH
     SNKYKQFHDF LAIITYLDWA MVLVTTLSCC SMLWESPWPT TGENLIFNNF YLQIAEYIFV
     LVMSFELVVK CIANGLFFTP KALVTDVGDI LTIFIYIVSC FILSFPLIVI TFQTSLIFVI
     WMPNHIEINS WAQLLMICRA SRPLRVYALI PHIRRVVVEL CRGFREILLV TILLVVLMFI
     FASFGVQLVG GKLASCNDPM ITTRENCTGL YDVKLFVTRM EVYGKHDNAM HPSIVVPRVW
     TNPRNFNFDH IGNAMLALFE TLSYKGWNVV RDILYLRHGA WAVLFIHIYV FIGCMIGLTL
     FVGVVVANYT ENRGTALLTV DQRRWHDLKA RLKMAQPLHV PPKPPESAKL RCYLYDLTTS
     RWFKQLFAAL VVLNSFTLVI PWNVSEEQDR KTFLLSLTVI SAICNILFTL ECLLKMIAFT
     LSGFWQSRRN RIDFIITILG INWIVFHFLF QLPAYFAGGI KEWKRLTYTY GYLVVILRFF
     TIAGRKSTLK MLMLTVVMSM VRSSFIIAAM FLLVLFYANA GVVLFGMVKY GQAVGKHVNF
     RNGREALVVL FRSVTGEDWN DIMHDCMRAP PFCNWHPGLS YWQTDCGNYV GAIVYFCSFY
     LIITYIVLNL LVAIIMENFS LFYSSEEDAL LSYADIRNFQ LVWNMVDTEQ KRSIPVRRVK
     FLLRLLKGRL EVTGEDDGLL FKHMCHEMER LHNGDDVSFH DVLNMLSYRS VDIRKNLQLE
     ELLQREELEY IIEEEVAKHT IRTWLENCLK NIKARQNNTL GKMSSIGSTF AFPQSQDLLT
     KGVVLTEASP DEESLQGDKG SGKKKASRGN SITEIVTEAQ KKSVKRGAEK IKERRGTLRQ
     MQMGTYDELE EVEEDEDTDA EIRRSSFEYS GVDMIQMSHE KQLEDVKTWW TLCD
//
DBGET integrated database retrieval system