ID E3N8K2_CAERE Unreviewed; 370 AA.
AC E3N8K2;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=One cut domain family member {ECO:0000256|RuleBase:RU361129};
GN ORFNames=CRE_18161 {ECO:0000313|EMBL:EFO89515.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the CUT homeobox family.
CC {ECO:0000256|ARBA:ARBA00008190, ECO:0000256|RuleBase:RU361129}.
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DR EMBL; DS268557; EFO89515.1; -; Genomic_DNA.
DR RefSeq; XP_003095279.1; XM_003095231.1.
DR AlphaFoldDB; E3N8K2; -.
DR EnsemblMetazoa; CRE18161.1; CRE18161.1; WBGene00065226.
DR GeneID; 9807429; -.
DR KEGG; crq:GCK72_021331; -.
DR CTD; 9807429; -.
DR eggNOG; KOG2252; Eukaryota.
DR HOGENOM; CLU_748507_0_0_1; -.
DR InParanoid; E3N8K2; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR003350; CUT_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR PANTHER; PTHR14057:SF32; HOMEOBOX PROTEIN ONECUT; 1.
DR PANTHER; PTHR14057; TRANSCRIPTION FACTOR ONECUT; 1.
DR Pfam; PF02376; CUT; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM01109; CUT; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS51042; CUT; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transcription {ECO:0000256|RuleBase:RU361129};
KW Transcription regulation {ECO:0000256|RuleBase:RU361129}.
FT DOMAIN 208..294
FT /note="CUT"
FT /evidence="ECO:0000259|PROSITE:PS51042"
FT DOMAIN 305..365
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 307..366
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 163..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 43768 MW; CC48CA935AE42748 CRC64;
MMSARGFNIP GPWHLKEEDR EQWMIEHYGY SGASFMYEVE DPLRGPLDPL HNNEDLFQED
REGHKFVGNL EETTNARNWS IRNADGTEVP SHRINYAHMK TWTDEDDAWL YRENTEDTHK
FVGNLETARE EYMRNQYPAD NEPLYAEETL RRIDYDEDDA WLNREMPEDP DSSESEIEES
DVVSQTQKQK TRRSSKKPST VTNDASDPLN APTPDYIDTK PLCGTVWSIL KEYGISQTLF
AQVVAQRRQG TMSDLLRNPR DWFKMKSGRD VYRRMYNWVR MAAHERLEIL NRDTPPVEPR
RKKLTDGKSK RHTFKPEEKA MLQAVFARNE RPDEDEMYEI AKQLDVKYDI IRIYFTNARR
RKSNVPSRIQ
//
