ID E3NB49_CAERE Unreviewed; 1167 AA.
AC E3NB49;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=BK channel {ECO:0000256|ARBA:ARBA00029579};
GN Name=Cre-slo-1 {ECO:0000313|EMBL:EFO91801.1};
GN ORFNames=CRE_07777 {ECO:0000313|EMBL:EFO91801.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS268582; EFO91801.1; -; Genomic_DNA.
DR RefSeq; XP_003094347.1; XM_003094299.1.
DR AlphaFoldDB; E3NB49; -.
DR STRING; 31234.E3NB49; -.
DR EnsemblMetazoa; CRE07777.1; CRE07777.1; WBGene00069806.
DR eggNOG; KOG1420; Eukaryota.
DR HOGENOM; CLU_006846_0_0_1; -.
DR InParanoid; E3NB49; -.
DR OMA; YWCKQCH; -.
DR OrthoDB; 2902976at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048735; Slowpoke-like_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF33; CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1; 1.
DR Pfam; PF03493; BK_channel_a; 2.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF21014; Slowpoke_C; 1.
DR PRINTS; PR01449; BKCHANNELA.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 48..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..361
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 511..570
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT DOMAIN 571..621
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT DOMAIN 1035..1151
FT /note="Ca2+-activated K+ channel Slowpoke-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21014"
SQ SEQUENCE 1167 AA; 132611 MW; 42F7C7C06BE3185F CRC64;
MGEIYSPSQS KGFNQPYGYP MNCNLSRVFM EMTEEDRKCL EERKYWCFLL SSITTFCASM
ILVVIWRVVT HLCCQRRERE FPEPVPPPEV VAINMNGSKH IGGEADPFLK QQQEEKHLGW
MTEAKDWAGE LISGQSLTGR FLVLLVFILS IGSLIIYFYD ASFQNFQVET CIPWQDSPSQ
QIDLGFNIFF LVYFFIRFIA ASDKVWFLLE MYSWIDFFTI PPSFVAIYLQ RNWLGFRFLR
ALRLMTVPDI LQYLNILKTS SSIRLTQLVT IFVAVCLTGA GLVHLLENSG DFFKGFINPH
RITYADSVYF VLVTMSTVGY GDIYCTTLCG RLFMIFFILF GLAMFASYVP EIADLIGNRQ
KYGGEYKGEH GKKHIVVCGH ITYDSVSHFL QDFLHEDRDD VDVEVVFLHR VVPDLELEGL
FKRHFTKVEF FTGTVMDSLD LSRVKIGDAD ACLVLANKYS TNPDAEDAAN IMRVISIKNY
SSDIRVIVQL MQYHNKAYLL NIPSWDWRRG DDVICLAELK LGFIAQSCLA PGFSTMMANL
FAMRSFKTSP HTPLWLNDYL RGAGMEISRQ SQTTPDWLNL YLCGAGMEMY TDTLSHSFVG
MTFPEAVDLL FNRLGLLLLA IELKDEENKE CNIAINPGPN IVIQPQTQGF FIAQSADEVK
RAFFWCKQCH DDIKDVSMIK KCKCKNLALF RRNTKHSTTA RARATEVLQQ FQPTIPPGTQ
MGPMGHLGQQ VQLRMINQQS STSDTHLNTK SLRFAYEIKK LMPSSGGRRN SMSIPPDGRG
VDFSKDFEQQ FQDMKYDSTG MFHWCPSRNL EDCVLERHQA AMTVLNGHVV VCLFADQDSP
LIGLRNFIMP LRSSNFHYHE LKHVVIVGDL EYLRKEWKTL YNLPKISILN GSPLSRADLR
AVNINLCDMC VIISARVPNT EDTTLADKEA ILASLNIKAM QFDDTLGFFP MRHQTGDRSP
LGSPISMQKK GAKFGTNVPM ITELVNDSNV QFLDQDDDDD PDTELYLTQP FACGTAFAIS
VLDSLMSTTY FNDSALTLIR TLVTGGATPE LELILAEGAG LRGGYSTPET LSNRDRCRIA
QISLSDKPYE GVGHNTTYGS MFTIALRRYG QLCIGLYRLH DQDNPDSMKR YVITNPPAEL
RIKNTDYVYV LEQFDPGLEY EPGKRQF
//
