ID E3NEW7_CAERE Unreviewed; 894 AA.
AC E3NEW7;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=CRE-TRP-2 protein {ECO:0000313|EMBL:EFO95659.1};
GN Name=Cre-trp-2 {ECO:0000313|EMBL:EFO95659.1};
GN ORFNames=CRE_13737 {ECO:0000313|EMBL:EFO95659.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS268628; EFO95659.1; -; Genomic_DNA.
DR RefSeq; XP_003093051.1; XM_003093003.1.
DR AlphaFoldDB; E3NEW7; -.
DR STRING; 31234.E3NEW7; -.
DR EnsemblMetazoa; CRE13737.1; CRE13737.1; WBGene00066833.
DR eggNOG; KOG3609; Eukaryota.
DR HOGENOM; CLU_005716_4_1_1; -.
DR InParanoid; E3NEW7; -.
DR OMA; KGIRCAE; -.
DR OrthoDB; 5406916at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF54; TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08344; TRP_2; 1.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 179..241
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 894 AA; 103276 MW; FDEE2F0E7AD65A53 CRC64;
MSSSVSVSEF RMIEDDDEKD GGSTSWMDSD SSRLREKQFL LSCERGDIGS VRKLLAGIST
ENFNINCLDP LGRNALLIAI ENENIEMIEL LLDHNIETGD AILYAIGEEN VEAVEIIVEH
LEKMDKFDAE RQGVEITEHS AFTPDITPIV LAAHKDNYEC IKLFLDKKGT VPHPHDVRCS
CPECYVAREE DSLRLSRSRI NAYRALTSPS LICLSARDPI LYAFELSWEL KRLSFIENEF
RTDYEELSQK CQKFCVHMLD QVRGSKELEV VLNHTTNAWH DVTSANGGNP EKLARLKLAI
QLSQKRFVAH PNCQQLLLDI WYEGVESVRC TNFIYKLIFY LLGMMSFPLF SLVYLLAPHS
SMGQFAKKPF IKFLSHSGSY IFFLILLIMA SQRMNVIDNL LRTDDVDRKE TRGPPPTVIE
CAIFLWVLGL IWVEIKQLWE CGLYNYCRNL WNILDFITNS LYLCTTALRV VSYVQVEIEA
LQPNSVHIAR HLPRRDWDAW DPTLLSECFF ATANIFSSLK LVHIFTVSPH LGPLKISLGR
MVIDIVKFFM VYALVLFAFA CGLNQLLWYY ASMRQNECNL YEQYKNEKSL SYKYEHLKES
CDDKYKSCSS IYHTAETLFW ALFGLVDLTH FRLKEDHFLS EWTGKTIFGS YCCCSIIVLL
NMLIAMMSNS YQYISDQADI EWKFARSRLF LEYFDDTATL PPPFNIVPSP KSIYYCLNYL
TKKLCNCTKL QQPGKQKSMR NQKILRSVND RENNYRFVTR NLVQRYIAQM QRMKQQSEGV
SEDDVNEIKQ DISAFRYELL GILRNAGYQT GHTDINQKTS SRNKKKTAMA ERRLKNSALL
HQEFPVPQMF QSGQRNMSIS SIHSNGRFKK SPLQKQAHTS FDTSSLNDDT DELL
//
