ID   E3NVA8_CAERE            Unreviewed;       226 AA.
AC   E3NVA8;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Glutathione S-transferase family protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CRE_06262 {ECO:0000313|EMBL:EFO97634.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=glutathione + RX = a halide anion + an S-substituted
CC         glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925,
CC         ChEBI:CHEBI:90779; EC=2.5.1.18;
CC         Evidence={ECO:0000256|ARBA:ARBA00000710};
CC   -!- SIMILARITY: Belongs to the GST superfamily. Omega family.
CC       {ECO:0000256|ARBA:ARBA00011067}.
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DR   EMBL; DS270877; EFO97634.1; -; Genomic_DNA.
DR   RefSeq; XP_003087662.1; XM_003087614.1.
DR   AlphaFoldDB; E3NVA8; -.
DR   STRING; 31234.E3NVA8; -.
DR   EnsemblMetazoa; CRE06262.1; CRE06262.1; WBGene00075364.
DR   eggNOG; KOG0406; Eukaryota.
DR   HOGENOM; CLU_011226_9_3_1; -.
DR   InParanoid; E3NVA8; -.
DR   OMA; TWTTKGE; -.
DR   OrthoDB; 767442at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR   CDD; cd00299; GST_C_family; 1.
DR   CDD; cd00570; GST_N_family; 1.
DR   Gene3D; 1.20.1050.10; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR045073; Omega/Tau-like.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR43968; -; 1.
DR   PANTHER; PTHR43968:SF15; GLUTATHIONE TRANSFERASE; 1.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF13409; GST_N_2; 1.
DR   SFLD; SFLDG01152; Main.3:_Omega-_and_Tau-like; 1.
DR   SFLD; SFLDG00358; Main_(cytGST); 1.
DR   SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT   DOMAIN          8..86
FT                   /note="GST N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50404"
FT   DOMAIN          90..220
FT                   /note="GST C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50405"
SQ   SEQUENCE   226 AA;  25771 MW;  E97C6D4893125295 CRC64;
     MEEHIMSPHL ILVSHVLCPY VQRAVIVLKE KGVCFERRDV DLANKPDWFK ACSPLGKTPV
     LLVDDVRIFE SAVICEYLED TLTPRLHPND ALIRAQHRAW MAFGSSMLNS IGAFYNAKND
     TALDVQAELI RAQLVQVEAE LVNGPWFAGE HFSLVDAVFG PVFRYFDVFD RLGDFHFFDD
     LPKTKAWRTA LAERASVREA AHPDYQILLR ESLCKRDSAL SRRVKV
//