ID E3QDS0_COLGM Unreviewed; 466 AA.
AC E3QDS0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:EFQ29008.1};
GN ORFNames=GLRG_04152 {ECO:0000313|EMBL:EFQ29008.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
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DR EMBL; GG697343; EFQ29008.1; -; Genomic_DNA.
DR RefSeq; XP_008093028.1; XM_008094837.1.
DR AlphaFoldDB; E3QDS0; -.
DR STRING; 645133.E3QDS0; -.
DR EnsemblFungi; EFQ29008; EFQ29008; GLRG_04152.
DR GeneID; 24409517; -.
DR VEuPathDB; FungiDB:GLRG_04152; -.
DR eggNOG; KOG0172; Eukaryota.
DR HOGENOM; CLU_016207_3_1_1; -.
DR OrthoDB; 2184985at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782}.
FT DOMAIN 6..140
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 144..459
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 466 AA; 51630 MW; 9F8B0B3343DFBCD7 CRC64;
MPDNKILVLG SGSVAKPCVD YLLRNERNKL TIGPHSLLRQ ISYLAQLTTQ TQRAVPGPPR
RRWRQTTYEP WPIALDVASP ELDAHVAAHD LVISLVPFIH HPTVIKAGIR GKTHVVTTSY
VSPGTRELEG EAMAAGITVL NEVGVDPGVD HLYAIKASGE VHRKGGKIKE FHSYCGGLPA
PECADNPLRF KFSCSPHGYL LSQFNSASYL QDGKVVDISN RDLMARAGPY HVADGHSFVA
YPNRNSVPFR EFYNIPEAET VARGSLRYEG NPSFVAALIK LGWLDRQPRD WLEKGNVDLT
LREVFGRIIC AHGSLIARVD ELCSFPNGAE RGRIISGLRW IGLFSENPAT LRRNPLHTLW
AELERLLSFQ PGERDLVMLQ HKFVIQWEDG RKETRTSTLE LLGDPEGHSA MAKLVGLTCG
IATQLLLDGE PALNVPGVLV PYTEDICNPI RNKLEDEGIK LVEKTL
//
