ID E3QGR9_COLGM Unreviewed; 1184 AA.
AC E3QGR9;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012485};
DE EC=2.3.2.26 {ECO:0000256|ARBA:ARBA00012485};
GN ORFNames=GLRG_05201 {ECO:0000313|EMBL:EFQ30057.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
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DR EMBL; GG697347; EFQ30057.1; -; Genomic_DNA.
DR RefSeq; XP_008094077.1; XM_008095886.1.
DR AlphaFoldDB; E3QGR9; -.
DR STRING; 645133.E3QGR9; -.
DR EnsemblFungi; EFQ30057; EFQ30057; GLRG_05201.
DR GeneID; 24410566; -.
DR VEuPathDB; FungiDB:GLRG_05201; -.
DR eggNOG; KOG0941; Eukaryota.
DR HOGENOM; CLU_002173_5_1_1; -.
DR OrthoDB; 5471864at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR PANTHER; PTHR45700:SF2; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008782};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 836..1184
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 1..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 1152
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 1184 AA; 133234 MW; 85C3A223B653C0D8 CRC64;
MAPWSQRHAP PHRPPVLRQT SADLITRVHT PSLTAPPGQL GRLPDYAILD SPHLQADSSS
SESDFHPRRP RRLTHSRSMS HPFPSLFSSK KKRTGAAPDT DSEDDAPVMT KPPGNSTHKR
GGTNGGSRDF ATGNCMTCGS LVRWPRELKV FKCTVCVTIN DIHPDTQGTR ANSGPKWLQR
PSQDSPSPQK QPTPPAERYD ARPISLEQTK RLIRQCIHAH LLKALRRSSS SEDECCENVD
KHASSSILRE QNGRPCTVRT TGVPQHKREK SQGNGSTYVF PEQPTLRPGT LRVPPTTRSF
SSSYPERPSM RQLTTEGSVP QPTDPAYWDV DYPKRIFKPL EDYITTCFSS FHCVNSSFLS
RRSAMPARSG SESTSRRPAV AKPEAKHAEH YTESPICDLD PKLLLLGDFA ENGTWWAGNQ
GPDRVRPKRS ASQRTEEVPS FITPRSPQVE WNDVVEWYRS VINAAESWMS IYEELTRESG
AEPLSATELR ALESQLLFGQ DHAHRTLLKA TETLLKRPGR PMTDPEDLRY LLIILDNPLL
HGESNTFQGR RSVDRRPSLA SDEALRADRP TLKTGPVSGQ HSVVIKRILG LISNSSSSCQ
NYLTTWFARF SEQRFIKIKD LAAGFLTYRL IRQNEKKHEV KVDITAGLIP SMSAGHSTAS
LHAALGTQRG TSKKQREQPK KMVYNDDWQI RAAARVLSLV FAANNMTHIR RPDQTSRNMS
SSTHRGGIQA HGQIIPTSDF YNTMIDYTDL VAEFEAWESK RGRFSFCQYP FLLSIWAKSQ
ILEHDARRQQ MTKARDAFFD SIMTRRTITQ FLVLDVRREC LVDDSLKAVS EVIGSGSEDI
KKGLRIVFKG EEGLDAGGLK KEWFLLLVRE VFNPEHVGMF IYDEDSQFCY FNPNSFETSD
QFFLVGVVLG LAIYNSTILD VALPPFAFRK LLASAPTAWA GPSAHPRPTM NYTLEDLAEY
RPRLAAGLRQ LLEYDGNVET TFQLDFVVDV EKYGTVMQVP LCPGGETKPV TNANRGEYVG
LHVRYLLETA VARQFEPFKR GFYTVCGGNA LSLFRPEEIE LLVRGSDTAL DVDALRGVAE
YDNWGTRNPD GVEPVVGWFW DTFKDASPDK QRKLLSFITG TDRVPAIGAA LLPIKITCLG
DDEDRYPIAR TCFNMLALRR YETRERLERM LWTAVHESEG FGLK
//
