ID E3QHZ5_COLGM Unreviewed; 1096 AA.
AC E3QHZ5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=GLRG_05627 {ECO:0000313|EMBL:EFQ30483.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC {ECO:0000256|ARBA:ARBA00009340}.
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DR EMBL; GG697349; EFQ30483.1; -; Genomic_DNA.
DR RefSeq; XP_008094503.1; XM_008096312.1.
DR AlphaFoldDB; E3QHZ5; -.
DR STRING; 645133.E3QHZ5; -.
DR EnsemblFungi; EFQ30483; EFQ30483; GLRG_05627.
DR GeneID; 24410992; -.
DR VEuPathDB; FungiDB:GLRG_05627; -.
DR eggNOG; KOG2171; Eukaryota.
DR HOGENOM; CLU_003794_0_1_1; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:EnsemblFungi.
DR GO; GO:0008139; F:nuclear localization sequence binding; IEA:EnsemblFungi.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0006606; P:protein import into nucleus; IEA:EnsemblFungi.
DR GO; GO:0007088; P:regulation of mitotic nuclear division; IEA:EnsemblFungi.
DR GO; GO:0060188; P:regulation of protein desumoylation; IEA:EnsemblFungi.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR040928; Importin_rep_5.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR024687; MMS19_C.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18816; Importin_rep_5; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR Pfam; PF12460; MMS19_C; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 30..110
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 179..217
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1096 AA; 121535 MW; CE64A21BFD21ECF9 CRC64;
MSVLPPDVHA ELSQLLQALQ SPDNSVRTQA EEHLQNNWTA NRPEVLLMGL AEQIQVAPDA
SIRSFAAVIF RRISSKSRKN ARGELVDMFL SLSQDQAAAI RQKLLECLGG DFQRAVRNKI
SDAVAEVARQ YTENNDSWPE LLGGLFQLSI APDAEKRETA FRVFATTPGI IEKQHEDTII
QAFQKGFKDD SVQVRLAAME AFAAFFRSLG KKVQPKFYPL IPDVLNILPP IKETHDSEDL
SSALVALIDL AESAPKMFKP LFHNLVQFSV SVIQDKELDN LCRQNALELM ATFADFAPSV
CRKDATYTND MITQCLSLMT DLGEDDDDAA EWLASDDLDQ EESDQNHVAG EQCMDRLANK
LGGQTILAPT FNWLPRMMTS MAWRDRHAAL MAISAISEGC RELMIGELSQ VLDLVVPALK
DPHPRVRWAG CNALGQMSTD FAPKMQTDYY DRVLKAIIPV LESPEARVKS HAAAALVNFC
EEAEKSILEP YLDELLAHLF QLLQNEKRYV QEQALSTIAT IADAAEAAFS KYYDTLMPLL
VSVLQRENDK EFRLLRAKAM ECATLIALAV GKERLGQDAM TLVQLLASIQ QNITDPDDPQ
AQYLMHCWGR MCRVLGQEFL PFLPNVMPPL LELASAKADI QLLDDDDQVE QIQQEDGWEL
VPLKGKMIGI RTSTMEDKNM AIELLVVYAQ VLEGSFAPYV AEIMEKIALP GLAFFFHDPV
RFISAKLVPQ LLSSYKKTYG SPSNELNGLW AATVDKLLEV LTAEPAIDTL AEMYQCFYES
VEVVGKECLS AEHLSRFIDS VHSAIEDYKD RVAQRLEDKE GVAAEDAEDD ADDVLLAIED
DQTLLSDMNK AFHAIFKNHG AAFLPAWERL LPTYEGFLKS DDPTQRQWGL CIMDDVLEYC
GPESQKYANL ITQPLVDGCR DSSPAIRQAA AYGIGVAAHR GGLPWAQFLG GALPFLFQVT
QVPDARSEDN VYATENACAA IAKILHYNAG SVQDPNNVVA QWMETLPVTN DEEAAPYAYA
YLAELIDKQH PAVVNQAGRV FVLTAQALEA DTLQGQTASR VVGAIKALLS QAGVDPTPLL
QQFSPESQRA ITAYFS
//
