ID E3R4U6_9LACO Unreviewed; 212 AA.
AC E3R4U6;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=3-dehydro-L-gulonate-6-phosphate decarboxylase {ECO:0000313|EMBL:EFQ44354.1};
DE EC=4.1.1.85 {ECO:0000313|EMBL:EFQ44354.1};
GN Name=sgbH {ECO:0000313|EMBL:EFQ44354.1};
GN ORFNames=LBKG_01378 {ECO:0000313|EMBL:EFQ44354.1};
OS Lactobacillus crispatus CTV-05.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=440496 {ECO:0000313|EMBL:EFQ44354.1, ECO:0000313|Proteomes:UP000005124};
RN [1] {ECO:0000313|EMBL:EFQ44354.1, ECO:0000313|Proteomes:UP000005124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CTV-05 {ECO:0000313|EMBL:EFQ44354.1,
RC ECO:0000313|Proteomes:UP000005124};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease.;
RA Ward D., Xu Q., Earl A., Liu Y., Feldgarden M., Gevers D., Young S.K.,
RA Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D., Howarth C., Jen D., Larson L., Mehta T.,
RA Neiman D., Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lactobacillus crispatus strain CTV-05.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL531739; EFQ44354.1; -; Genomic_DNA.
DR RefSeq; WP_005727951.1; NZ_GL531739.1.
DR AlphaFoldDB; E3R4U6; -.
DR HOGENOM; CLU_081825_0_0_9; -.
DR Proteomes; UP000005124; Unassembled WGS sequence.
DR GO; GO:0033982; F:3-dehydro-L-gulonate-6-phosphate decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:InterPro.
DR GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd04726; KGPDC_HPS; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR041710; HPS/KGPDC.
DR InterPro; IPR001754; OMPdeCOase_dom.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR PANTHER; PTHR35039; 3-KETO-L-GULONATE-6-PHOSPHATE DECARBOXYLASE SGBH-RELATED; 1.
DR PANTHER; PTHR35039:SF3; 3-KETO-L-GULONATE-6-PHOSPHATE DECARBOXYLASE SGBH-RELATED; 1.
DR Pfam; PF00215; OMPdecase; 1.
DR SMART; SM00934; OMPdecase; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:EFQ44354.1};
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563}.
FT DOMAIN 5..203
FT /note="Orotidine 5'-phosphate decarboxylase"
FT /evidence="ECO:0000259|SMART:SM00934"
SQ SEQUENCE 212 AA; 23458 MW; 306A0BD95BDC8197 CRC64;
MALPMLQVAL DCESTAEALN VARQVMDQVD VLETGTILCY QDGVKAVSAL RAVGPDKIVL
ADVKCADAGT KFGKASKDAG ADWMTCINAA TVPTMVNARK KIEVQVELYE GWDNKERMQE
WLNNGIDQVV YHQSRDAKFA GQKWGEKDVA NVKALIDMGF KVSVTGGVHP EVLKLFKDLP
VYCFIAGRDI RNAEDPHARA KQYKDEIKRI WG
//
