ID   E3RIM2_PYRTT            Unreviewed;       632 AA.
AC   E3RIM2;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=L-ornithine N(5)-monooxygenase {ECO:0000256|ARBA:ARBA00018612};
DE            EC=1.14.13.196 {ECO:0000256|ARBA:ARBA00012881};
DE   AltName: Full=L-ornithine N(5)-oxygenase {ECO:0000256|ARBA:ARBA00030351};
GN   ORFNames=PTT_07895 {ECO:0000313|EMBL:EFQ94419.1};
OS   Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus)
OS   (Drechslera teres f. teres).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC   Pyrenophora.
OX   NCBI_TaxID=861557 {ECO:0000313|Proteomes:UP000001067};
RN   [1] {ECO:0000313|EMBL:EFQ94419.1, ECO:0000313|Proteomes:UP000001067}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0-1 {ECO:0000313|EMBL:EFQ94419.1,
RC   ECO:0000313|Proteomes:UP000001067};
RX   PubMed=21067574; DOI=10.1186/gb-2010-11-11-r109;
RA   Ellwood S.R., Liu Z., Syme R.A., Lai Z., Hane J.K., Keiper F., Moffat C.S.,
RA   Oliver R.P., Friesen T.L.;
RT   "A first genome assembly of the barley fungal pathogen Pyrenophora teres f.
RT   teres.";
RL   Genome Biol. 11:R109.1-R109.14(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-ornithine + NADH + O2 = H2O + N(5)-hydroxy-L-ornithine +
CC         NAD(+); Xref=Rhea:RHEA:41512, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:46911, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:78275; EC=1.14.13.196;
CC         Evidence={ECO:0000256|ARBA:ARBA00001398};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-ornithine + NADPH + O2 = H2O + N(5)-hydroxy-L-ornithine +
CC         NADP(+); Xref=Rhea:RHEA:41508, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:46911, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC         ChEBI:CHEBI:78275; EC=1.14.13.196;
CC         Evidence={ECO:0000256|ARBA:ARBA00001847};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC   -!- SIMILARITY: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-
CC       oxygenase family. {ECO:0000256|ARBA:ARBA00007588}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL533333; EFQ94419.1; -; Genomic_DNA.
DR   RefSeq; XP_003297477.1; XM_003297429.1.
DR   AlphaFoldDB; E3RIM2; -.
DR   EnsemblFungi; EFQ94419; EFQ94419; PTT_07895.
DR   KEGG; pte:PTT_07895; -.
DR   eggNOG; KOG1399; Eukaryota.
DR   HOGENOM; CLU_006937_7_0_1; -.
DR   OrthoDB; 49786at2759; -.
DR   Proteomes; UP000001067; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR025700; Lys/Orn_oxygenase.
DR   PANTHER; PTHR42877; -; 1.
DR   PANTHER; PTHR42877:SF5; L-ORNITHINE N(5)-OXYGENASE; 1.
DR   Pfam; PF13434; Lys_Orn_oxgnase; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001067}.
SQ   SEQUENCE   632 AA;  71122 MW;  33329A2C5570B872 CRC64;
     MLPGSPAETI RHINGYSESA CTYIPVVIIG AGAGGIATGC QLKEKLGFDQ FRIFDRHGGI
     GGTWWINRYP GVGCDISAVL YSFSFAPNPN WSSFFPPGEE IQQYFSDVCT KYEIGDKFQF
     NVEVDECRWL DEEQLWEIKI SHLVPGIGDK SARHRQKLWE EHGERAIIVH RETIRTKVIC
     SAVGGMGEPQ IWPEHIPGIE RFQGPIFHSA RWEEHDMKDK NIIVLGTGCS AAQLVPKLTQ
     APYHAKSVTQ LMRSPPWVVP ETVPARENVK LNNHLLKAAR NVPFFLWLLR QAVAAGNEYD
     FRLFGSNTWA QKERLRTESH LRDAIKKSTP EKYHDMLTPK YSVGCKRRVF GGNWFEGLRD
     PKINLTTQPL TEVRERTVVI GPGRTYPDPA DRSSAAPSDR QELSADMIIT ANGFRVLHWA
     HPLRIYGRHG HNLIDVMNAR GGPQAYQGTA MDGFPNLFIT IGPNTANGHT SILIAIENQV
     QYSLKFISQI LAGDATLVEV KKSAEMAYTQ RIQAALKDMI WTRGGCTSFY FMENGWNPTV
     YPWSQMHFTY RCMFPVWSDW DISYTTKGLW KRRVGGVAKL VVLTALMVAA VNVVTKPQVW
     NVQHGIMLAQ SGLRSILQRG IGALGMVQAQ LN
//