ID E4KZT7_9FIRM Unreviewed; 419 AA.
AC E4KZT7;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Serine protease do-like protein {ECO:0000313|EMBL:EFR32642.1};
GN ORFNames=HMPREF9286_0456 {ECO:0000313|EMBL:EFR32642.1};
OS Peptoniphilus harei ACS-146-V-Sch2b.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Peptoniphilus.
OX NCBI_TaxID=908338 {ECO:0000313|EMBL:EFR32642.1, ECO:0000313|Proteomes:UP000003705};
RN [1] {ECO:0000313|EMBL:EFR32642.1, ECO:0000313|Proteomes:UP000003705}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-146-V-Sch2b {ECO:0000313|EMBL:EFR32642.1,
RC ECO:0000313|Proteomes:UP000003705};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFR32642.1}.
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DR EMBL; AENP01000024; EFR32642.1; -; Genomic_DNA.
DR RefSeq; WP_005957342.1; NZ_AENP01000024.1.
DR AlphaFoldDB; E4KZT7; -.
DR eggNOG; COG0265; Bacteria.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000003705; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:EFR32642.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003705};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 270..362
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 381..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 419 AA; 44922 MW; B9E4B01C30B07962 CRC64;
MKKNDNLNKN PGMGKIVIII ALVFSLIGGI IGSAITTYKL LPQGESKTSN SDSNITISAK
DNVSVASAVA KKAMSSVVGI TTKGVQQSFF GQVEVQGVGS GVIVDPKGYI LTNAHVVKLN
NQVVKDVTVR LNNEKDIQGK TIWADEMIDL AIVKINTDEK LNAASLGDSD ALSIGDTAIA
IGNPISLQFS QTVTQGIISG LDRYVGAVSG GGYMTGLIQT DASINGGNSG GALLNAEGEV
IGINTVKVQS AEGLGFSIPI NFIKPIIKQV IETGKYKEMS MGMLTMNVDV AAQVLNEKPS
VDKGIFVYKV YDGSPAAAAG LEAGDIVTRI GKDQVSDNNA LKSILYKYQV GDKVEIEYVR
NGKKMTTEVS FTDYSIENDK EAQKDLRAQN REKSAEEEAR ARRQEEFFNR FRQEFGNNF
//
