ID E4M7X6_9BACT Unreviewed; 499 AA.
AC E4M7X6;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Peptidase Do {ECO:0000313|EMBL:EFR58961.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:EFR58961.1};
GN Name=mucD {ECO:0000313|EMBL:EFR58961.1};
GN ORFNames=HMPREF9720_1141 {ECO:0000313|EMBL:EFR58961.1};
OS Alistipes sp. HGB5.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=908612 {ECO:0000313|EMBL:EFR58961.1, ECO:0000313|Proteomes:UP000002960};
RN [1] {ECO:0000313|EMBL:EFR58961.1, ECO:0000313|Proteomes:UP000002960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGB5 {ECO:0000313|EMBL:EFR58961.1,
RC ECO:0000313|Proteomes:UP000002960};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFR58961.1}.
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DR EMBL; AENZ01000008; EFR58961.1; -; Genomic_DNA.
DR AlphaFoldDB; E4M7X6; -.
DR PATRIC; fig|908612.3.peg.237; -.
DR eggNOG; COG0265; Bacteria.
DR Proteomes; UP000002960; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFR58961.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..499
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003184523"
FT DOMAIN 315..386
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 140
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 170
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 247
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 499 AA; 53585 MW; D134271E7D16E39B CRC64;
MNLNTCYRIM KKAFLILGAV AVSAAAGGLT AWAVAGGREG SVQYIEREVE RTPALGTQFT
SYQAEQYPDL TYAAENAVKA VVNIEAVQQV EMPRRRGYDP FLEFFGIPQG YDEGPQFREQ
RAGGSGVIIS ADGYVVTNNH VVDGASKLRV KLNDGRSFDA KLIGKDSATD LALLKIEASD
LPTLTFGSSD ALRLGEWVLA IGSPFDLQST ITAGIVSAKA RNLGVIPNDF RIEAFIQTDA
AVNPGNSGGA LVNTHGELVG INTLIKSQTG SYIGYSFAIP ESIVRKVVVD LKEFGIVQRA
LLGIRFAIVD QDFIDREGKE LGITELGGAY VAGVVEGGSA SEAGIRKGDV ILDIDGVKIN
DNATLSEQIG RRRPNDKVKL SVKRDGAVKQ IEVTLRNKAG KTELMTKEDV DVVEVLGGKF
ADAGTKLCRE LDIKGGVQVV GIKADGILAR ARVKQGFVIT HINDRPVYSV ADMQRMDEKV
RSIDGIYPNG RAASYTLVE
//
