ID   E4MZV8_KITSK            Unreviewed;       560 AA.
AC   E4MZV8;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE            EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN   OrderedLocusNames=KSE_42570 {ECO:0000313|EMBL:BAJ30042.1};
OS   Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS   / NBRC 14216 / KM-6054) (Streptomyces setae).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ30042.1, ECO:0000313|Proteomes:UP000007076};
RN   [1] {ECO:0000313|EMBL:BAJ30042.1, ECO:0000313|Proteomes:UP000007076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC   KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX   PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA   Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA   Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA   Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA   Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA   Takahashi Y., Fujita N.;
RT   "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT   snapshot of the family Streptomycetaceae.";
RL   DNA Res. 17:393-406(2010).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC       {ECO:0000256|RuleBase:RU004453}.
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DR   EMBL; AP010968; BAJ30042.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4MZV8; -.
DR   SMR; E4MZV8; -.
DR   STRING; 452652.KSE_42570; -.
DR   CAZy; CBM16; Carbohydrate-Binding Module Family 16.
DR   CAZy; GH18; Glycoside Hydrolase Family 18.
DR   KEGG; ksk:KSE_42570; -.
DR   PATRIC; fig|452652.3.peg.4251; -.
DR   eggNOG; COG3469; Bacteria.
DR   HOGENOM; CLU_019399_1_1_11; -.
DR   Proteomes; UP000007076; Chromosome.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd02871; GH18_chitinase_D-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR003305; CenC_carb-bd.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR45708; ENDOCHITINASE; 1.
DR   PANTHER; PTHR45708:SF49; ENDOCHITINASE; 1.
DR   Pfam; PF02018; CBM_4_9; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS01095; GH18_1; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT   DOMAIN          254..560
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
FT   REGION          179..256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..237
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   560 AA;  57002 MW;  F5DD14ABBFF432E3 CRC64;
     MERAAQARRV SHAAASGPSA AKRTLAGVSA AAVIGAGLAV AGSVTASADV ANLIANAGFE
     SGLSNWTCTS GSGAAVVSSP VHGGTAALKA TPSGQDSAQC SQTVSVQPNS QYTLSGFVQG
     SYVYLGATGT GVNASTWAPG NASYGQLSTT FSTGASTTSV TVFVHGWYGQ PAFYADDLVL
     SGPGGSSPSP STSAPTSQPP TSQPPTSQPP TSQPPTSQPP TSQPPTSQPP TSQPPTSNPP
     GDATCATKPR PTGKVLQGYW ENWDGASNGV HPGLGWTPIT DSRIGQHGYN VVTTAFPVIL
     SDGTALWQDG MDTGVKVPTP AEMCQAKANG ATILMSIGGA AAGIDLSSSA VADKFVATLV
     PILKKYNYDG IDIDIETGLS GSGSIGTLSA SQSNLIRIID GVLAQMPAGF GLTMAPETAY
     VTGGSVTYGS IWGSYLPIIK KYVDNGQLWW LNMQYYNGSM YGCSGDSYSA GTVQGFTAQT
     TCLNNGLTIQ GTTIKVPYDK QVPGLPAQPG AGGGYMAPSL VSQAYGSFNG QLKGLMTWSL
     NWDGSKGWTF GDNVKALQGR
//