ID E4N5E4_KITSK Unreviewed; 488 AA.
AC E4N5E4;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Putative decarboxylase {ECO:0000313|EMBL:BAJ26425.1};
GN OrderedLocusNames=KSE_05820 {ECO:0000313|EMBL:BAJ26425.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26425.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ26425.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP010968; BAJ26425.1; -; Genomic_DNA.
DR RefSeq; WP_014133744.1; NC_016109.1.
DR AlphaFoldDB; E4N5E4; -.
DR STRING; 452652.KSE_05820; -.
DR KEGG; ksk:KSE_05820; -.
DR PATRIC; fig|452652.3.peg.575; -.
DR eggNOG; COG1982; Bacteria.
DR HOGENOM; CLU_025925_2_1_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR43277:SF4; ARGININE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT DOMAIN 7..302
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 415..464
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
SQ SEQUENCE 488 AA; 51532 MW; 430E0AA1E6773F86 CRC64;
MDQSQAPVLE ALAAFHANPP TVFTPPGHKQ GRGADPRVLA VLGAEVFRSD VLATGGLDDR
TGSHGVLPHA QALMAEAVGA EHTFFSTCGS SLSVKAAMLA VAGPHEELLV GRDAHKSVVA
GLILAGISPI WVDPCWDADL HLAHPPRAEA FRVALERHPE ARGALVTSPT PYGTCADLAG
IAEVCHAAGK PLIVDEAWGA HLPFHPDLPQ WAMDAGADVC VTSVHKMGSG LEQGSVFHLR
GDLVAPDALK QREDLLGTTS PSVLVYAALD GWRRQMVQHG RDLYGAALAL AADTRERIGA
LDGLRVHGRD DFCGPRLAAD LDPLQVVVDV SGLGTTGYRA GDWLRSHHRL TLHVCDHRRI
SAQLTHADDP ATADALLHGL RGLAAAADTL RPAARVRVPD PAELRLPQAA LPRDAFFGPT
EQVPPARAVG RIAAEMLTPY PPGIPAVLPG ERLNHAVLDY LRTGLDAGML VPDSADPDLA
TVKVAREP
//
