ID E4N5T1_KITSK Unreviewed; 377 AA.
AC E4N5T1;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN OrderedLocusNames=KSE_07220 {ECO:0000313|EMBL:BAJ26562.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26562.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ26562.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
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DR EMBL; AP010968; BAJ26562.1; -; Genomic_DNA.
DR RefSeq; WP_014133881.1; NC_016109.1.
DR AlphaFoldDB; E4N5T1; -.
DR STRING; 452652.KSE_07220; -.
DR KEGG; ksk:KSE_07220; -.
DR PATRIC; fig|452652.3.peg.711; -.
DR eggNOG; COG2518; Bacteria.
DR HOGENOM; CLU_037629_0_1_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR026448; Methyltr_grasp.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04188; methyltr_grsp; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:BAJ26562.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076};
KW Transferase {ECO:0000313|EMBL:BAJ26562.1}.
SQ SEQUENCE 377 AA; 40154 MW; 09D1B5EE5F3BC767 CRC64;
MSTSAELRAA LVDGFTGDDM VTDPAWDRAA KSVPRELFVG SYFLPVEGSV PTEYRPVQEG
EPGWLAGVYT NQTLITQLDG RARPEDGKAS GSPSSSSTLP SLVLRMWHQL DTEAGHRVLE
IGTGTGYSTA LGAYRLGDAN VTSIEYDQAV GEAAAAALKS AGHAPRLIIG DGLLGDPDGG
EYDRLIATCS VRYIPQPWLY QVKPGGKILV TLSGWSYGFG LALLTVTEPG SAMGRFLPGY
TSFMIARPHD RPPRQNLALL PGDERPTRID PEIIGTWTGG WVAQLAAPSA ERMGAGGQQI
LSDVATGSQA RTMPNPDGGW TVVQRGPLRL WDQVETAVEA WQAVGVPHQD GFGITVSPHG
QRVWIGSEAG PGWNLPI
//
