ID   E4N7A1_KITSK            Unreviewed;       700 AA.
AC   E4N7A1;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Putative Clp family protein {ECO:0000313|EMBL:BAJ27082.1};
GN   OrderedLocusNames=KSE_12490 {ECO:0000313|EMBL:BAJ27082.1};
OS   Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS   / NBRC 14216 / KM-6054) (Streptomyces setae).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ27082.1, ECO:0000313|Proteomes:UP000007076};
RN   [1] {ECO:0000313|EMBL:BAJ27082.1, ECO:0000313|Proteomes:UP000007076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC   KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX   PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA   Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA   Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA   Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA   Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA   Takahashi Y., Fujita N.;
RT   "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT   snapshot of the family Streptomycetaceae.";
RL   DNA Res. 17:393-406(2010).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; AP010968; BAJ27082.1; -; Genomic_DNA.
DR   RefSeq; WP_014134400.1; NC_016109.1.
DR   AlphaFoldDB; E4N7A1; -.
DR   STRING; 452652.KSE_12490; -.
DR   KEGG; ksk:KSE_12490; -.
DR   PATRIC; fig|452652.3.peg.1247; -.
DR   eggNOG; COG0542; Bacteria.
DR   HOGENOM; CLU_005070_9_4_11; -.
DR   Proteomes; UP000007076; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT   DOMAIN          382..560
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          371..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..385
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   700 AA;  75178 MW;  0ACC1E03209EB1C4 CRC64;
     MSADPVDVSK SGKTDGTGAG GTDDADEVAR RRAALPSWVR ELELSLAVHP QVLFTGNVRD
     QYLLPSDLPH CRSPRLAPFD LAGVVDAVCR ARGYGALAAV DQVTDHIAVR LLAGTPDEMP
     PVIRELVAAD ARSARAKEAG EEDEEPALTD RLRDVMVAAV RHPGPPIGLL VPYAARLGSA
     RAPAAGEVAR LFAAVEELGH TARPVRRGAA VGVYNTVFWV VERQEELPLE FPVGSRAVRV
     ISVPAPPHDQ RLAAARHVVE AVAARQDAAD RPDPAGRETA ARALADSSHG MGSSEVMAIG
     RMAVDRGLPT HRLEEAARLY RVGVTDNPWA TEALRDRIRD GEEFLNARVI GQPHAVRRTL
     EIFMRSAAGL SGAQSSSSPN RPRGTLFLSG PTGVGKTELA KGIAEMILGK DARPIRFDMS
     EFAEEHARDR LIGAPPGYVG HDAGGELTNA VRASPMSVLL FDEIDKANPR LFDLFLQILE
     DGRLTDGRGA TVYFTECVLI FTSNLGVAAS AQRAEDARTG GGDGTGNGTG NGTGDGPDGG
     APAEHRPGTV RRLTRHDDPT TVRLALRDAF DLFFNDQIKR PELRNRFGDN FIPMDFMQEK
     WVPLILDKAI AAVAGRVLEV HGATLEIGED AWEVLRMEAG ARLDHGGRGI LTAVESALVN
     PLSREVFRNP PRRGERIEVT AVEGDGEADG YTVEVTRWPS
//