ID E4NJS4_KITSK Unreviewed; 218 AA.
AC E4NJS4;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Putative acyltransferase {ECO:0000313|EMBL:BAJ33222.1};
DE EC=2.3.1.- {ECO:0000313|EMBL:BAJ33222.1};
GN OrderedLocusNames=KSE_74670 {ECO:0000313|EMBL:BAJ33222.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ33222.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ33222.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
CC -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid
CC by incorporating acyl moiety at the 2 position.
CC {ECO:0000256|ARBA:ARBA00037183}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-
CC sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC ChEBI:CHEBI:58608; EC=2.3.1.51;
CC Evidence={ECO:0000256|ARBA:ARBA00001141};
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DR EMBL; AP010968; BAJ33222.1; -; Genomic_DNA.
DR RefSeq; WP_014140513.1; NC_016109.1.
DR AlphaFoldDB; E4NJS4; -.
DR STRING; 452652.KSE_74670; -.
DR KEGG; ksk:KSE_74670; -.
DR PATRIC; fig|452652.3.peg.7514; -.
DR eggNOG; COG0204; Bacteria.
DR HOGENOM; CLU_027938_4_1_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10434; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10434:SF60; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE LPAT1, CHLOROPLASTIC; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:BAJ33222.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076};
KW Transferase {ECO:0000313|EMBL:BAJ33222.1}.
FT DOMAIN 30..150
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 218 AA; 22232 MW; 73167C69D52B2CFA CRC64;
MLSAVARAVV PLLGRFTFSA DEDAVLAPGS IVAANHSSLI DPGLVLAAVS RLGVEPVVLA
TAGLWRIPLL GGALAREGHV PVHRGTARAA RALDDAAAAL AAGRVVVIYP EGRLPRRVDA
ADTPPGPFRS GLARLAADGA PVVPLGQAGA RRISSGSTAK QVAGVLTAPL RRPRVHVHLG
APLRLDGDDV PTATARARTA VTDAWRTAAD RLAAAQRG
//
